Isolation and Characterization of a Novel Lytic Bacteriophage against the K2 Capsule-Expressing Hypervirulent <i>Klebsiella pneumoniae</i> Strain 52145, and Identification of Its Functional Depolymerase

Isolation and Characterization of a Novel Lytic Bacteriophage against the K2 Capsule-Expressing Hypervirulent <i>Klebsiella pneumoniae</i> Strain 52145, and Identification of Its Functional Depolymerase

<i>Klebsiella pneumoniae</i> is among the leading bacteria that cause nosocomial infections. The capsule of this Gram-negative bacterium is a dominant virulence factor, with a prominent role in defense and biofilm formation. Bacteriophages, which are specific for one bacterial strain and...

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Bibliographic Details
Main Authors: Botond Zsombor Pertics, Alysia Cox, Adrienn Nyúl, Nóra Szamek, Tamás Kovács, György Schneider
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Microorganisms
Subjects:
<i>Klebsiella pneumoniae</i>
K2 serotype
bacteriophage
tail fibers
capsule depolymerase
Online Access:https://www.mdpi.com/2076-2607/9/3/650

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