Growth inhibitory effect and Chk1-dependent signaling involved in G2/M arrest on human gastric cancer cells induced by diallyl disulfide

Diallyl disulfide (DADS) inhibits growth and induces cell cycle G2/M arrest in human gastric cancer MGC803 cells. In this study, 15 mg/L DADS exerted similar effects on growth and cell cycle arrest in human gastric cancer BGC823 cells. Due to the importance of cell cycle redistribution in DADS-media...

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Bibliographic Details
Main Authors: H. Ling, L. Wen, X.X. Ji, Y.L. Tang, J. He, H. Tan, H. Xia, J.G. Zhou, Q. Su
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2010-03-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000300008