Indirect co-culture with tendons or tenocytes can program amniotic epithelial cells towards stepwise tenogenic differentiation.

BACKGROUND: Amniotic epithelial cells (AEC) have potential applications in cell-based therapy. Thus far their ability to differentiate into tenocytes has not been investigated although a cell source providing a large supply of tenocytes remains a priority target of regenerative medicine in order to...

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Bibliographic Details
Main Authors: Barbara Barboni, Valentina Curini, Valentina Russo, Annunziata Mauro, Oriana Di Giacinto, Marco Marchisio, Melissa Alfonsi, Mauro Mattioli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3277591?pdf=render