Aerosol Emissions from Heated Tobacco Products: A Review Focusing on Carbonyls, Analytical Methods, and Experimental Quality
We provide an extensive review of 17 independent and industry-funded studies targeting carbonyls in aerosol emissions of Heated Tobacco Products (HTPs), focusing on quality criteria based on the reproducibility of experiments, appropriate analytic methods, and puffing regimes. Most revised studies c...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-11-01
|
Series: | Toxics |
Subjects: | |
Online Access: | https://www.mdpi.com/2305-6304/11/12/947 |
_version_ | 1797379263236669440 |
---|---|
author | Roberto A. Sussman Federica Sipala Rosalia Emma Simone Ronsisvalle |
author_facet | Roberto A. Sussman Federica Sipala Rosalia Emma Simone Ronsisvalle |
author_sort | Roberto A. Sussman |
collection | DOAJ |
description | We provide an extensive review of 17 independent and industry-funded studies targeting carbonyls in aerosol emissions of Heated Tobacco Products (HTPs), focusing on quality criteria based on the reproducibility of experiments, appropriate analytic methods, and puffing regimes. Most revised studies complied with these requirements, but some were unreproducible, while others failed to consider analytical variables that may have affected the results and/or produced unrealistic comparisons. We also provide a review of the literature on the physicochemical properties of heated tobacco and HTP aerosols, as well as the evaluation of HTPs by regulatory agencies, addressing various critiques of their relative safety profile. The outcomes from the revised studies and regulatory evaluations tend to agree with and converge to a general consensus that HTP aerosols expose users to significantly lower levels of toxicity than tobacco smoke. |
first_indexed | 2024-03-08T20:19:38Z |
format | Article |
id | doaj.art-fba54d78c50f4240b5b72e6f8d4f16c1 |
institution | Directory Open Access Journal |
issn | 2305-6304 |
language | English |
last_indexed | 2024-03-08T20:19:38Z |
publishDate | 2023-11-01 |
publisher | MDPI AG |
record_format | Article |
series | Toxics |
spelling | doaj.art-fba54d78c50f4240b5b72e6f8d4f16c12023-12-22T14:45:56ZengMDPI AGToxics2305-63042023-11-01111294710.3390/toxics11120947Aerosol Emissions from Heated Tobacco Products: A Review Focusing on Carbonyls, Analytical Methods, and Experimental QualityRoberto A. Sussman0Federica Sipala1Rosalia Emma2Simone Ronsisvalle3Institute of Physical Sciences, National Autonomous University of Mexico UNAM, Mexico City 04510, MexicoDepartment of Drug and Health Sciences, University of Catania, 95123 Catania, ItalyCenter of Excellence for the Acceleration of Harm Reduction (CoEHAR), 95123 Catania, ItalyDepartment of Drug and Health Sciences, University of Catania, 95123 Catania, ItalyWe provide an extensive review of 17 independent and industry-funded studies targeting carbonyls in aerosol emissions of Heated Tobacco Products (HTPs), focusing on quality criteria based on the reproducibility of experiments, appropriate analytic methods, and puffing regimes. Most revised studies complied with these requirements, but some were unreproducible, while others failed to consider analytical variables that may have affected the results and/or produced unrealistic comparisons. We also provide a review of the literature on the physicochemical properties of heated tobacco and HTP aerosols, as well as the evaluation of HTPs by regulatory agencies, addressing various critiques of their relative safety profile. The outcomes from the revised studies and regulatory evaluations tend to agree with and converge to a general consensus that HTP aerosols expose users to significantly lower levels of toxicity than tobacco smoke.https://www.mdpi.com/2305-6304/11/12/947heated tobacco productscarbonylsaerosolsanalytical methods |
spellingShingle | Roberto A. Sussman Federica Sipala Rosalia Emma Simone Ronsisvalle Aerosol Emissions from Heated Tobacco Products: A Review Focusing on Carbonyls, Analytical Methods, and Experimental Quality Toxics heated tobacco products carbonyls aerosols analytical methods |
title | Aerosol Emissions from Heated Tobacco Products: A Review Focusing on Carbonyls, Analytical Methods, and Experimental Quality |
title_full | Aerosol Emissions from Heated Tobacco Products: A Review Focusing on Carbonyls, Analytical Methods, and Experimental Quality |
title_fullStr | Aerosol Emissions from Heated Tobacco Products: A Review Focusing on Carbonyls, Analytical Methods, and Experimental Quality |
title_full_unstemmed | Aerosol Emissions from Heated Tobacco Products: A Review Focusing on Carbonyls, Analytical Methods, and Experimental Quality |
title_short | Aerosol Emissions from Heated Tobacco Products: A Review Focusing on Carbonyls, Analytical Methods, and Experimental Quality |
title_sort | aerosol emissions from heated tobacco products a review focusing on carbonyls analytical methods and experimental quality |
topic | heated tobacco products carbonyls aerosols analytical methods |
url | https://www.mdpi.com/2305-6304/11/12/947 |
work_keys_str_mv | AT robertoasussman aerosolemissionsfromheatedtobaccoproductsareviewfocusingoncarbonylsanalyticalmethodsandexperimentalquality AT federicasipala aerosolemissionsfromheatedtobaccoproductsareviewfocusingoncarbonylsanalyticalmethodsandexperimentalquality AT rosaliaemma aerosolemissionsfromheatedtobaccoproductsareviewfocusingoncarbonylsanalyticalmethodsandexperimentalquality AT simoneronsisvalle aerosolemissionsfromheatedtobaccoproductsareviewfocusingoncarbonylsanalyticalmethodsandexperimentalquality |