Epoxy Cross-Linked Collagen and Collagen-Laminin Peptide Hydrogels as Corneal Substitutes

Epoxy Cross-Linked Collagen and Collagen-Laminin Peptide Hydrogels as Corneal Substitutes

A bi-functional epoxy-based cross-linker, 1,4-Butanediol diglycidyl ether (BDDGE), was investigated in the fabrication of collagen based corneal substitutes. Two synthetic strategies were explored in the preparation of the cross-linked collagen scaffolds. The lysine residues of Type 1 porcine collag...

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Bibliographic Details
Main Authors: May Griffith, Bo Liedberg, Jaywant Phopase, William. Bruce Jackson, Per Fagerholm, Silvia Odorcic, Kimberley Merrett, Christopher W. Noel, Debbie Mitra, Li Buay Koh, Mohammad Mirazul Islam
Format: Article
Language:English
Published: MDPI AG 2013-08-01
Series:Journal of Functional Biomaterials
Subjects:
biomimetic materials
cross-linking
collagen
cornea
tissue engineering
Online Access:http://www.mdpi.com/2079-4983/4/3/162

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