Mitochondrial medicine - a key to solve pathophysiology of 21 century diseases

Over the past 13 years mitochondrial defects have been involved in wide variety of degenerative diseases - Parkinson disease, Alzheimer dementia, arteriosclerosis, ageing and cancer. Mitochondria are believed to control apoptosis or programmed cell death. Disturbance in mitochondrial metabolism has...

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Main Authors: Emina Kiseljaković, Radivoj Jadrić, Sabaheta Hasić, Lorenka Ljuboja, Jovo Radovanović, Husein Kulenović, Mira Winterhalter-Jadrić
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2008-02-01
Series:Biomolecules & Biomedicine
Subjects:
Online Access:https://www.bjbms.org/ojs/index.php/bjbms/article/view/3580
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author Emina Kiseljaković
Radivoj Jadrić
Sabaheta Hasić
Lorenka Ljuboja
Jovo Radovanović
Husein Kulenović
Mira Winterhalter-Jadrić
author_facet Emina Kiseljaković
Radivoj Jadrić
Sabaheta Hasić
Lorenka Ljuboja
Jovo Radovanović
Husein Kulenović
Mira Winterhalter-Jadrić
author_sort Emina Kiseljaković
collection DOAJ
description Over the past 13 years mitochondrial defects have been involved in wide variety of degenerative diseases - Parkinson disease, Alzheimer dementia, arteriosclerosis, ageing and cancer. Mitochondria are believed to control apoptosis or programmed cell death. Disturbance in mitochondrial metabolism has also been implicated in many common diseases such as congestive hart failure, diabetes and migraine. Scientific investigations have showed complexities in mitochondrial genetics, but at the same time, pathophysiology of mitochondrial diseases is still enigma. Mitochondria and their DNAs are opening the era of "mitochondrial medicine". What we today call "a mitochondrial medicine" is only a part of the whole panorama of diseases based on disordered mitochondrial function.
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spelling doaj.art-fbaa1d782db64dcb89afc6bc6e5a0d002024-03-15T14:38:04ZengAssociation of Basic Medical Sciences of Federation of Bosnia and HerzegovinaBiomolecules & Biomedicine2831-08962831-090X2008-02-0121-210.17305/bjbms.2002.3580933Mitochondrial medicine - a key to solve pathophysiology of 21 century diseasesEmina Kiseljaković0Radivoj Jadrić1Sabaheta Hasić2Lorenka Ljuboja3Jovo Radovanović4Husein Kulenović5Mira Winterhalter-Jadrić6Institute for Physiology and Biochemistry, Department of Biochemistry, Faculty of MedicineInstitute for Physiology and Biochemistry, Department of Biochemistry, Faculty of MedicineInstitute for Physiology and Biochemistry, Department of Biochemistry, Faculty of MedicineInstitute for Physiology and Biochemistry, Department of Biochemistry, Faculty of MedicineInstitute for Physiology and Biochemistry, Department of Biochemistry, Faculty of MedicineInstitute for Physiology and Biochemistry, Department of Biochemistry, Faculty of MedicineInstitute for Physiology and Biochemistry, Department of Biochemistry, Faculty of Medicine Over the past 13 years mitochondrial defects have been involved in wide variety of degenerative diseases - Parkinson disease, Alzheimer dementia, arteriosclerosis, ageing and cancer. Mitochondria are believed to control apoptosis or programmed cell death. Disturbance in mitochondrial metabolism has also been implicated in many common diseases such as congestive hart failure, diabetes and migraine. Scientific investigations have showed complexities in mitochondrial genetics, but at the same time, pathophysiology of mitochondrial diseases is still enigma. Mitochondria and their DNAs are opening the era of "mitochondrial medicine". What we today call "a mitochondrial medicine" is only a part of the whole panorama of diseases based on disordered mitochondrial function. https://www.bjbms.org/ojs/index.php/bjbms/article/view/3580mitochondriamtDNAmitochondrial diseases
spellingShingle Emina Kiseljaković
Radivoj Jadrić
Sabaheta Hasić
Lorenka Ljuboja
Jovo Radovanović
Husein Kulenović
Mira Winterhalter-Jadrić
Mitochondrial medicine - a key to solve pathophysiology of 21 century diseases
Biomolecules & Biomedicine
mitochondria
mtDNA
mitochondrial diseases
title Mitochondrial medicine - a key to solve pathophysiology of 21 century diseases
title_full Mitochondrial medicine - a key to solve pathophysiology of 21 century diseases
title_fullStr Mitochondrial medicine - a key to solve pathophysiology of 21 century diseases
title_full_unstemmed Mitochondrial medicine - a key to solve pathophysiology of 21 century diseases
title_short Mitochondrial medicine - a key to solve pathophysiology of 21 century diseases
title_sort mitochondrial medicine a key to solve pathophysiology of 21 century diseases
topic mitochondria
mtDNA
mitochondrial diseases
url https://www.bjbms.org/ojs/index.php/bjbms/article/view/3580
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AT jovoradovanovic mitochondrialmedicineakeytosolvepathophysiologyof21centurydiseases
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