Lethality of Zinc Oxide Nanoparticles Surpasses Conventional Zinc Oxide via Oxidative Stress, Mitochondrial Damage and Calcium Overload: A Comparative Hepatotoxicity Study

Lethality of Zinc Oxide Nanoparticles Surpasses Conventional Zinc Oxide via Oxidative Stress, Mitochondrial Damage and Calcium Overload: A Comparative Hepatotoxicity Study

Zinc oxide nanoparticles (ZnO NPs) with high bioavailability and excellent physicochemical properties are gradually becoming commonplace as a substitute for conventional ZnO materials. The present study aimed to investigate the hepatotoxicity mechanism of ZnO NPs and traditional non-nano ZnO particl...

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Bibliographic Details
Main Authors: Xingyao Pei, Haiyang Jiang, Gang Xu, Cun Li, Daowen Li, Shusheng Tang
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
zinc oxide nanoparticles
ZnO
hepatotoxicity
RNA-seq
oxidative stress
Online Access:https://www.mdpi.com/1422-0067/23/12/6724

Internet

https://www.mdpi.com/1422-0067/23/12/6724

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