Survival of Split Thickness Skin Graft in Diabetic and Non-diabetic Wound Management
Introduction: Split skin grafting is widely used surgical procedure for the treatment of ulcers. Graft survival depends on number of factors like vascularity, wound infection etc. diabetes is associated with endothelial dysfunction, neuropathy, wound infection which collectively affect the graf...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Pvt. Ltd.
2016-01-01
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| Series: | International Journal of Anatomy Radiology and Surgery |
| Subjects: | |
| Online Access: | http://www.ijars.net/articles/PDF/2094/5-%2017170_F(P)_PF1(Vsu_Om)PFA(Om)_PF2(PVSU).pdf |
| Summary: | Introduction: Split skin grafting is widely used surgical
procedure for the treatment of ulcers. Graft survival
depends on number of factors like vascularity, wound
infection etc. diabetes is associated with endothelial
dysfunction, neuropathy, wound infection which
collectively affect the graft survival.
Aim: To compare the amount of graft uptake, the
post operative complications and survival of split
thickness skin graft in diabetic and non diabetic wound
management.
Materials and Methods: In our prospective nonrandomized comparative study total 104 patients with
ulcer were included of which 52 were diabetic and 52 were
non-diabetic. All of them underwent split skin grafting as
part of their wound management. Comparison was made
between two groups in terms of amount of graft uptake,
post operative wound infection, re-ulceration, revisional
surgery, donor site infection.
Results: Average wound surface area in diabetic group
is 42.31 cm2
and average graft uptake is 23.67 cm2
, in
non-diabetic group average wound surface area is 78.06
cm2
and average graft uptake is 64.06 cm2
. Compared
with non-diabetics, diabetics have significantly less
graft uptake (p<0.001). out of 52 patients in diabetic
group 10(19.3%) underwent revisional surgery, out of
52 patients in non-diabetic group 2(3.85%) patients
underwent revisional surgery (p value is <0.05) which
is statistically significant. 3(5.8%) out of 52 patients in
diabetic group developed re-ulceration, 1(1.9%) out of
52 in non-diabetic group developed re-ulceration (p
>0.3, not significant). 13(25%) out of 52 in diabetic group
developed post operative graft infection, 7(13.5%) out
of 52 in non-diabetic group developed graft infection (p
> 0.1, not significant). None of the patients in the study
developed donor site infection.
Conclusion: Diabetes is associated with poor graft
survival and high post operative complication rates in
patients undergoing split skin grafting. |
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| ISSN: | 2277-8543 2455-6874 |