Survival of Split Thickness Skin Graft in Diabetic and Non-diabetic Wound Management

Introduction: Split skin grafting is widely used surgical procedure for the treatment of ulcers. Graft survival depends on number of factors like vascularity, wound infection etc. diabetes is associated with endothelial dysfunction, neuropathy, wound infection which collectively affect the graf...

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Main Authors: Maramreddy Revanth, Shibumon Madhavan Mundundackal, B.K. Shivaprasad Rai, Sunil Kumar Sajjan, Pullareddy Seelam
Format: Article
Language:English
Published: JCDR Research and Publications Pvt. Ltd. 2016-01-01
Series:International Journal of Anatomy Radiology and Surgery
Subjects:
Online Access:http://www.ijars.net/articles/PDF/2094/5-%2017170_F(P)_PF1(Vsu_Om)PFA(Om)_PF2(PVSU).pdf
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author Maramreddy Revanth
Shibumon Madhavan Mundundackal
B.K. Shivaprasad Rai
Sunil Kumar Sajjan
Pullareddy Seelam
author_facet Maramreddy Revanth
Shibumon Madhavan Mundundackal
B.K. Shivaprasad Rai
Sunil Kumar Sajjan
Pullareddy Seelam
author_sort Maramreddy Revanth
collection DOAJ
description Introduction: Split skin grafting is widely used surgical procedure for the treatment of ulcers. Graft survival depends on number of factors like vascularity, wound infection etc. diabetes is associated with endothelial dysfunction, neuropathy, wound infection which collectively affect the graft survival. Aim: To compare the amount of graft uptake, the post operative complications and survival of split thickness skin graft in diabetic and non diabetic wound management. Materials and Methods: In our prospective nonrandomized comparative study total 104 patients with ulcer were included of which 52 were diabetic and 52 were non-diabetic. All of them underwent split skin grafting as part of their wound management. Comparison was made between two groups in terms of amount of graft uptake, post operative wound infection, re-ulceration, revisional surgery, donor site infection. Results: Average wound surface area in diabetic group is 42.31 cm2 and average graft uptake is 23.67 cm2 , in non-diabetic group average wound surface area is 78.06 cm2 and average graft uptake is 64.06 cm2 . Compared with non-diabetics, diabetics have significantly less graft uptake (p<0.001). out of 52 patients in diabetic group 10(19.3%) underwent revisional surgery, out of 52 patients in non-diabetic group 2(3.85%) patients underwent revisional surgery (p value is <0.05) which is statistically significant. 3(5.8%) out of 52 patients in diabetic group developed re-ulceration, 1(1.9%) out of 52 in non-diabetic group developed re-ulceration (p >0.3, not significant). 13(25%) out of 52 in diabetic group developed post operative graft infection, 7(13.5%) out of 52 in non-diabetic group developed graft infection (p > 0.1, not significant). None of the patients in the study developed donor site infection. Conclusion: Diabetes is associated with poor graft survival and high post operative complication rates in patients undergoing split skin grafting.
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spelling doaj.art-fbabe86ce28e4ea4b7131d84026651512022-12-21T21:55:50ZengJCDR Research and Publications Pvt. Ltd.International Journal of Anatomy Radiology and Surgery2277-85432455-68742016-01-0151202410.7860/IJARS/2016/17170:2094Survival of Split Thickness Skin Graft in Diabetic and Non-diabetic Wound Management Maramreddy Revanth0Shibumon Madhavan Mundundackal 1B.K. Shivaprasad Rai2Sunil Kumar Sajjan 3Pullareddy Seelam4Postgraduate, Department of General Surgery, KMC, Mangalore, Karnataka, India.Associate Professor, Department of General Surgery, KMC, Mangalore, Karnataka, India.Professor, Department of General Surgery, KMC, Mangalore, Karnataka, India.Postgraduate, Department of General Surgery, KMC, Mangalore, Karnataka, India.Postgraduate, Department of General Surgery, KMC, Mangalore, Karnataka, India.Introduction: Split skin grafting is widely used surgical procedure for the treatment of ulcers. Graft survival depends on number of factors like vascularity, wound infection etc. diabetes is associated with endothelial dysfunction, neuropathy, wound infection which collectively affect the graft survival. Aim: To compare the amount of graft uptake, the post operative complications and survival of split thickness skin graft in diabetic and non diabetic wound management. Materials and Methods: In our prospective nonrandomized comparative study total 104 patients with ulcer were included of which 52 were diabetic and 52 were non-diabetic. All of them underwent split skin grafting as part of their wound management. Comparison was made between two groups in terms of amount of graft uptake, post operative wound infection, re-ulceration, revisional surgery, donor site infection. Results: Average wound surface area in diabetic group is 42.31 cm2 and average graft uptake is 23.67 cm2 , in non-diabetic group average wound surface area is 78.06 cm2 and average graft uptake is 64.06 cm2 . Compared with non-diabetics, diabetics have significantly less graft uptake (p<0.001). out of 52 patients in diabetic group 10(19.3%) underwent revisional surgery, out of 52 patients in non-diabetic group 2(3.85%) patients underwent revisional surgery (p value is <0.05) which is statistically significant. 3(5.8%) out of 52 patients in diabetic group developed re-ulceration, 1(1.9%) out of 52 in non-diabetic group developed re-ulceration (p >0.3, not significant). 13(25%) out of 52 in diabetic group developed post operative graft infection, 7(13.5%) out of 52 in non-diabetic group developed graft infection (p > 0.1, not significant). None of the patients in the study developed donor site infection. Conclusion: Diabetes is associated with poor graft survival and high post operative complication rates in patients undergoing split skin grafting.http://www.ijars.net/articles/PDF/2094/5-%2017170_F(P)_PF1(Vsu_Om)PFA(Om)_PF2(PVSU).pdfgraft infectionmicroangiopathyrevisional surgery
spellingShingle Maramreddy Revanth
Shibumon Madhavan Mundundackal
B.K. Shivaprasad Rai
Sunil Kumar Sajjan
Pullareddy Seelam
Survival of Split Thickness Skin Graft in Diabetic and Non-diabetic Wound Management
International Journal of Anatomy Radiology and Surgery
graft infection
microangiopathy
revisional surgery
title Survival of Split Thickness Skin Graft in Diabetic and Non-diabetic Wound Management
title_full Survival of Split Thickness Skin Graft in Diabetic and Non-diabetic Wound Management
title_fullStr Survival of Split Thickness Skin Graft in Diabetic and Non-diabetic Wound Management
title_full_unstemmed Survival of Split Thickness Skin Graft in Diabetic and Non-diabetic Wound Management
title_short Survival of Split Thickness Skin Graft in Diabetic and Non-diabetic Wound Management
title_sort survival of split thickness skin graft in diabetic and non diabetic wound management
topic graft infection
microangiopathy
revisional surgery
url http://www.ijars.net/articles/PDF/2094/5-%2017170_F(P)_PF1(Vsu_Om)PFA(Om)_PF2(PVSU).pdf
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AT shibumonmadhavanmundundackal survivalofsplitthicknessskingraftindiabeticandnondiabeticwoundmanagement
AT bkshivaprasadrai survivalofsplitthicknessskingraftindiabeticandnondiabeticwoundmanagement
AT sunilkumarsajjan survivalofsplitthicknessskingraftindiabeticandnondiabeticwoundmanagement
AT pullareddyseelam survivalofsplitthicknessskingraftindiabeticandnondiabeticwoundmanagement