A New Oxygen Containing Pyclen-Type Ligand as a Manganese(II) Binder for MRI and <sup>52</sup>Mn PET Applications: Equilibrium, Kinetic, Relaxometric, Structural and Radiochemical Studies

A New Oxygen Containing Pyclen-Type Ligand as a Manganese(II) Binder for MRI and <sup>52</sup>Mn PET Applications: Equilibrium, Kinetic, Relaxometric, Structural and Radiochemical Studies

A new pyclen-3,9-diacetate derivative ligand (H<sub>2</sub><b>3,9-OPC2A</b>) was synthesized possessing an etheric O-atom opposite to the pyridine ring, to improve the dissociation kinetics of its Mn(II) complex (pyclen = 3,6,9,15-tetraazabicyclo(9.3.1)pentadeca-1(15),11,13-t...

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Bibliographic Details
Main Authors: Tibor Csupász, Dániel Szücs, Ferenc Krisztián Kálmán, Oldamur Hollóczki, Anikó Fekete, Dezső Szikra, Éva Tóth, Imre Tóth, Gyula Tircsó
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Molecules
Subjects:
manganese
magnetic resonance imaging
contrast agents
macrocycles
stability
dissociation kinetics
Online Access:https://www.mdpi.com/1420-3049/27/2/371

Internet

https://www.mdpi.com/1420-3049/27/2/371

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