Ploidy Variation and Spontaneous Haploid-Diploid Switching of Candida glabrata Clinical Isolates

Ploidy Variation and Spontaneous Haploid-Diploid Switching of Candida glabrata Clinical Isolates

ABSTRACT The human fungal pathogen Candida glabrata is phylogenetically closely related to Saccharomyces cerevisiae, a model eukaryotic organism. Unlike S. cerevisiae, which has both haploid and diploid forms and a complete sexual cycle, C. glabrata has long been considered a haploid and asexual spe...

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Bibliographic Details
Main Authors: Qiushi Zheng, Jing Liu, Juanxiu Qin, Bingjie Wang, Jian Bing, Han Du, Min Li, Fangyou Yu, Guanghua Huang
Format: Article
Language:English
Published: American Society for Microbiology 2022-08-01
Series:mSphere
Subjects:
diploidy
ploidy change
adaptation
Candida glabrata
clinical isolates
haploidy
Online Access:https://journals.asm.org/doi/10.1128/msphere.00260-22

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