Acetylated DNMT1 Downregulation and Related Regulatory Factors Influence Metastatic Melanoma Patients Survival

Acetylated DNMT1 Downregulation and Related Regulatory Factors Influence Metastatic Melanoma Patients Survival

The role of post-translational modifications (PTM) of the key epigenetic factor DNMT1 protein has not been well explored in cutaneous metastatic melanoma progression. The acetylated DNMT1 (ac-DNMT1) protein level was assessed using an anti-acetylated lysine antibody in a clinically annotated melanom...

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Bibliographic Details
Main Authors:	Xiaoqing Zhang, Matias A. Bustos, Yoshiaki Shoji, Romela Irene Ramos, Yuuki Iida, Rebecca Gentry, Teh-Ling Takeshima, Dave S. B. Hoon
Format:	Article
Language:	English
Published:	MDPI AG 2021-09-01
Series:	Cancers
Subjects:	acetylated-DNMT1 cutaneous metastatic melanoma DNMT1 panobinostat TIP60 USP7
Online Access:	https://www.mdpi.com/2072-6694/13/18/4691

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