Oxygen supplementation in anesthesia can block FLASH effect and anti-tumor immunity in conventional proton therapy

Oxygen supplementation in anesthesia can block FLASH effect and anti-tumor immunity in conventional proton therapy

Abstract Background Radiation-induced neurocognitive dysfunction is a major adverse effect of brain radiation therapy and has specific relevance in pediatric oncology, where serious cognitive deficits have been reported in survivors of pediatric brain tumors. Moreover, many pediatric patients receiv...

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Main Authors: Lorea Iturri, Annaïg Bertho, Charlotte Lamirault, Elise Brisebard, Marjorie Juchaux, Cristèle Gilbert, Julie Espenon, Catherine Sébrié, Laurène Jourdain, Ludovic de Marzi, Frédéric Pouzoulet, Jane Muret, Pierre Verrelle, Yolanda Prezado
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-023-00411-9

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https://doi.org/10.1038/s43856-023-00411-9

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