Cross-platform toxicogenomics for the prediction of non-genotoxic hepatocarcinogenesis in rat.

In the area of omics profiling in toxicology, i.e. toxicogenomics, characteristic molecular profiles have previously been incorporated into prediction models for early assessment of a carcinogenic potential and mechanism-based classification of compounds. Traditionally, the biomarker signatures used...

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Bibliographic Details
Main Authors: Michael Römer, Johannes Eichner, Ute Metzger, Markus F Templin, Simon Plummer, Heidrun Ellinger-Ziegelbauer, Andreas Zell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4022579?pdf=render