ANALYSIS ON THE INFLUENCE OF VARIOUS SUBSTANCES ON SELECTIVE ACTIVATION OF Ca²⁺-DEPENDENT NO-SYNTASE (REVIEW)
The article presents information on the structure, classification and functions of NO-synthases. The main inhibitors of the enzyme, as well as their mechanisms of action, are considered. Among the substances activating the activity of the enzyme, special attention was paid to substances of nucleotid...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | Russian |
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LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
2019-01-01
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| Series: | Разработка и регистрация лекарственных средств |
| Subjects: | |
| Online Access: | https://www.pharmjournal.ru/jour/article/view/629 |
| _version_ | 1826569784231198720 |
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| author | E. S. Kokareva V. V. Morozov Ya. M. Stanishevskiy M. A. Zhuravleva N. V. Nozdryukhina V. S. Orlova E. V. Orlova |
| author_facet | E. S. Kokareva V. V. Morozov Ya. M. Stanishevskiy M. A. Zhuravleva N. V. Nozdryukhina V. S. Orlova E. V. Orlova |
| author_sort | E. S. Kokareva |
| collection | DOAJ |
| description | The article presents information on the structure, classification and functions of NO-synthases. The main inhibitors of the enzyme, as well as their mechanisms of action, are considered. Among the substances activating the activity of the enzyme, special attention was paid to substances of nucleotide-peptide nature, using the example of a substance isolated from Saccharomyces cerevisiae race 14, it was found that the nucleotide preparation based on a substance isolated from Saccharomyces cerevisiae race 14. has a more pronounced activating action in comparison with T-activin, and helps to restore the functions of the enzyme in diseases such as diabetes. |
| first_indexed | 2024-04-10T01:40:51Z |
| format | Article |
| id | doaj.art-fbc371ce5a74449080c7d2075e08cf72 |
| institution | Directory Open Access Journal |
| issn | 2305-2066 2658-5049 |
| language | Russian |
| last_indexed | 2025-03-14T11:44:50Z |
| publishDate | 2019-01-01 |
| publisher | LLC Center of Pharmaceutical Analytics (LLC «CPHA») |
| record_format | Article |
| series | Разработка и регистрация лекарственных средств |
| spelling | doaj.art-fbc371ce5a74449080c7d2075e08cf722025-03-02T09:53:22ZrusLLC Center of Pharmaceutical Analytics (LLC «CPHA»)Разработка и регистрация лекарственных средств2305-20662658-50492019-01-01042328629ANALYSIS ON THE INFLUENCE OF VARIOUS SUBSTANCES ON SELECTIVE ACTIVATION OF Ca²⁺-DEPENDENT NO-SYNTASE (REVIEW)E. S. Kokareva0V. V. Morozov1Ya. M. Stanishevskiy2M. A. Zhuravleva3N. V. Nozdryukhina4V. S. Orlova5E. V. Orlova6Peoples’ Friendship University of Russia (RUDN University)Peoples’ Friendship University of Russia (RUDN University)Peoples’ Friendship University of Russia (RUDN University)Peoples’ Friendship University of Russia (RUDN University)Peoples’ Friendship University of Russia (RUDN University)Peoples’ Friendship University of Russia (RUDN University)Institute of Theoretical and Experimental Biophysics (ITEB) RASThe article presents information on the structure, classification and functions of NO-synthases. The main inhibitors of the enzyme, as well as their mechanisms of action, are considered. Among the substances activating the activity of the enzyme, special attention was paid to substances of nucleotide-peptide nature, using the example of a substance isolated from Saccharomyces cerevisiae race 14, it was found that the nucleotide preparation based on a substance isolated from Saccharomyces cerevisiae race 14. has a more pronounced activating action in comparison with T-activin, and helps to restore the functions of the enzyme in diseases such as diabetes.https://www.pharmjournal.ru/jour/article/view/629nitric oxide (ii)ca²⁺-dependent no-synthasenucleotides |
| spellingShingle | E. S. Kokareva V. V. Morozov Ya. M. Stanishevskiy M. A. Zhuravleva N. V. Nozdryukhina V. S. Orlova E. V. Orlova ANALYSIS ON THE INFLUENCE OF VARIOUS SUBSTANCES ON SELECTIVE ACTIVATION OF Ca²⁺-DEPENDENT NO-SYNTASE (REVIEW) Разработка и регистрация лекарственных средств nitric oxide (ii) ca²⁺-dependent no-synthase nucleotides |
| title | ANALYSIS ON THE INFLUENCE OF VARIOUS SUBSTANCES ON SELECTIVE ACTIVATION OF Ca²⁺-DEPENDENT NO-SYNTASE (REVIEW) |
| title_full | ANALYSIS ON THE INFLUENCE OF VARIOUS SUBSTANCES ON SELECTIVE ACTIVATION OF Ca²⁺-DEPENDENT NO-SYNTASE (REVIEW) |
| title_fullStr | ANALYSIS ON THE INFLUENCE OF VARIOUS SUBSTANCES ON SELECTIVE ACTIVATION OF Ca²⁺-DEPENDENT NO-SYNTASE (REVIEW) |
| title_full_unstemmed | ANALYSIS ON THE INFLUENCE OF VARIOUS SUBSTANCES ON SELECTIVE ACTIVATION OF Ca²⁺-DEPENDENT NO-SYNTASE (REVIEW) |
| title_short | ANALYSIS ON THE INFLUENCE OF VARIOUS SUBSTANCES ON SELECTIVE ACTIVATION OF Ca²⁺-DEPENDENT NO-SYNTASE (REVIEW) |
| title_sort | analysis on the influence of various substances on selective activation of ca²⁺ dependent no syntase review |
| topic | nitric oxide (ii) ca²⁺-dependent no-synthase nucleotides |
| url | https://www.pharmjournal.ru/jour/article/view/629 |
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