The characteristics and risk factors of in-stent restenosis in patients with percutaneous coronary intervention: what can we do
Abstract Background Percutaneous coronary intervention (PCI) is a common treatment for patients with coronary heart disease, and intra-stent restenosis (ISR) is a serious complication after PCI. It’s necessary to identify the potential risk factors to provide evidence for the prevention of ISR. Meth...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2020-12-01
|
| Series: | BMC Cardiovascular Disorders |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12872-020-01798-2 |
| _version_ | 1818875799197974528 |
|---|---|
| author | Pengfei Wang Haixia Qiao RuiJuan Wang Ruitian Hou Jingtao Guo |
| author_facet | Pengfei Wang Haixia Qiao RuiJuan Wang Ruitian Hou Jingtao Guo |
| author_sort | Pengfei Wang |
| collection | DOAJ |
| description | Abstract Background Percutaneous coronary intervention (PCI) is a common treatment for patients with coronary heart disease, and intra-stent restenosis (ISR) is a serious complication after PCI. It’s necessary to identify the potential risk factors to provide evidence for the prevention of ISR. Methods The patients who underwent coronary angiography 1 year after PCI in our hospital from January 2017 to May 2019 were selected. The characteristics and results of clinical examination of ISR and no-ISR patients were compared, Multivariate logistic regression analyses were performed to identify the risk factors. Results A total of 209 patients were included, the incidence of ISR after PCI was 30.62%. There were significant differences on the hypertension, diabetes, number of coronary artery lesions, reasons for stent implantation, the diameter of stent, the length of stent and stent position between ISR group and no-ISR patients (all p < 0.05). The LDL-C in ISR groups was significantly higher than that of no-ISR group (p = 0.048), there were no significant differences between two groups in FPG, TG, TC, HDL-C, Apo A1, Apo B, LP-a and glycated haemoglobin (all p > 0.05). The hypertension (OR 4.30, 95% CI 1.12–9.34), diabetes (OR 5.29, 95% CI 1.25–9.01), number of coronary artery lesions ≥ 2 (OR 4.84, 95% CI 1.21–9.55), LDL-C ≥ 1.9 mmol/L (OR 5.93, 95% CI 2.29–10.01), unstable angina (OR 2.92, 95% CI 1.20–4.55), left anterior descending artery (OR 4.01, 95% CI 1.73–7.58), diameter of stent ≥ 3 mm (OR 5.42, 95% CI 1.24–10.84), the length of stent > 20 mm (OR 3.06, 95% CI 1.19–5.22) were the independent risk factor for ISR (all p < 0.05). Conclusion It is necessary to take preventive measures against these risk factors to reduce ISR, and studies with larger sample size and longer follow-up on this issue are needed in the future. |
| first_indexed | 2024-12-19T13:32:14Z |
| format | Article |
| id | doaj.art-fbc40f8646ab4932b1bbadb35e5d483a |
| institution | Directory Open Access Journal |
| issn | 1471-2261 |
| language | English |
| last_indexed | 2024-12-19T13:32:14Z |
| publishDate | 2020-12-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cardiovascular Disorders |
| spelling | doaj.art-fbc40f8646ab4932b1bbadb35e5d483a2022-12-21T20:19:19ZengBMCBMC Cardiovascular Disorders1471-22612020-12-012011610.1186/s12872-020-01798-2The characteristics and risk factors of in-stent restenosis in patients with percutaneous coronary intervention: what can we doPengfei Wang0Haixia Qiao1RuiJuan Wang2Ruitian Hou3Jingtao Guo4Department of Cardiology, Affiliated Hospital of Chengde Medical CollegeDepartment of Cardiology, Chengde Central HospitalDepartment of Cardiology, Affiliated Hospital of Chengde Medical CollegeDepartment of Cardiology, Affiliated Hospital of Chengde Medical CollegeDepartment of Cardiology, Chengde Central HospitalAbstract Background Percutaneous coronary intervention (PCI) is a common treatment for patients with coronary heart disease, and intra-stent restenosis (ISR) is a serious complication after PCI. It’s necessary to identify the potential risk factors to provide evidence for the prevention of ISR. Methods The patients who underwent coronary angiography 1 year after PCI in our hospital from January 2017 to May 2019 were selected. The characteristics and results of clinical examination of ISR and no-ISR patients were compared, Multivariate logistic regression analyses were performed to identify the risk factors. Results A total of 209 patients were included, the incidence of ISR after PCI was 30.62%. There were significant differences on the hypertension, diabetes, number of coronary artery lesions, reasons for stent implantation, the diameter of stent, the length of stent and stent position between ISR group and no-ISR patients (all p < 0.05). The LDL-C in ISR groups was significantly higher than that of no-ISR group (p = 0.048), there were no significant differences between two groups in FPG, TG, TC, HDL-C, Apo A1, Apo B, LP-a and glycated haemoglobin (all p > 0.05). The hypertension (OR 4.30, 95% CI 1.12–9.34), diabetes (OR 5.29, 95% CI 1.25–9.01), number of coronary artery lesions ≥ 2 (OR 4.84, 95% CI 1.21–9.55), LDL-C ≥ 1.9 mmol/L (OR 5.93, 95% CI 2.29–10.01), unstable angina (OR 2.92, 95% CI 1.20–4.55), left anterior descending artery (OR 4.01, 95% CI 1.73–7.58), diameter of stent ≥ 3 mm (OR 5.42, 95% CI 1.24–10.84), the length of stent > 20 mm (OR 3.06, 95% CI 1.19–5.22) were the independent risk factor for ISR (all p < 0.05). Conclusion It is necessary to take preventive measures against these risk factors to reduce ISR, and studies with larger sample size and longer follow-up on this issue are needed in the future.https://doi.org/10.1186/s12872-020-01798-2In-stent restenosisPCICardiovascularRiskPreventionNursing |
| spellingShingle | Pengfei Wang Haixia Qiao RuiJuan Wang Ruitian Hou Jingtao Guo The characteristics and risk factors of in-stent restenosis in patients with percutaneous coronary intervention: what can we do BMC Cardiovascular Disorders In-stent restenosis PCI Cardiovascular Risk Prevention Nursing |
| title | The characteristics and risk factors of in-stent restenosis in patients with percutaneous coronary intervention: what can we do |
| title_full | The characteristics and risk factors of in-stent restenosis in patients with percutaneous coronary intervention: what can we do |
| title_fullStr | The characteristics and risk factors of in-stent restenosis in patients with percutaneous coronary intervention: what can we do |
| title_full_unstemmed | The characteristics and risk factors of in-stent restenosis in patients with percutaneous coronary intervention: what can we do |
| title_short | The characteristics and risk factors of in-stent restenosis in patients with percutaneous coronary intervention: what can we do |
| title_sort | characteristics and risk factors of in stent restenosis in patients with percutaneous coronary intervention what can we do |
| topic | In-stent restenosis PCI Cardiovascular Risk Prevention Nursing |
| url | https://doi.org/10.1186/s12872-020-01798-2 |
| work_keys_str_mv | AT pengfeiwang thecharacteristicsandriskfactorsofinstentrestenosisinpatientswithpercutaneouscoronaryinterventionwhatcanwedo AT haixiaqiao thecharacteristicsandriskfactorsofinstentrestenosisinpatientswithpercutaneouscoronaryinterventionwhatcanwedo AT ruijuanwang thecharacteristicsandriskfactorsofinstentrestenosisinpatientswithpercutaneouscoronaryinterventionwhatcanwedo AT ruitianhou thecharacteristicsandriskfactorsofinstentrestenosisinpatientswithpercutaneouscoronaryinterventionwhatcanwedo AT jingtaoguo thecharacteristicsandriskfactorsofinstentrestenosisinpatientswithpercutaneouscoronaryinterventionwhatcanwedo AT pengfeiwang characteristicsandriskfactorsofinstentrestenosisinpatientswithpercutaneouscoronaryinterventionwhatcanwedo AT haixiaqiao characteristicsandriskfactorsofinstentrestenosisinpatientswithpercutaneouscoronaryinterventionwhatcanwedo AT ruijuanwang characteristicsandriskfactorsofinstentrestenosisinpatientswithpercutaneouscoronaryinterventionwhatcanwedo AT ruitianhou characteristicsandriskfactorsofinstentrestenosisinpatientswithpercutaneouscoronaryinterventionwhatcanwedo AT jingtaoguo characteristicsandriskfactorsofinstentrestenosisinpatientswithpercutaneouscoronaryinterventionwhatcanwedo |