Engineering the oleaginous yeast Candida tropicalis for α-humulene overproduction

Engineering the oleaginous yeast Candida tropicalis for α-humulene overproduction

Abstract Background α-Humulene is a plant-derived monocyclic sesquiterpenoid with multiple pharmacological activities, and far-reaching potential for the development of new drugs. Currently, the production of α-humulene is typically achieved via plant extraction, which is not sustainable and limited...

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Bibliographic Details
Main Authors: Lihua Zhang, Haiquan Yang, Yuanyuan Xia, Wei Shen, Liming Liu, Qi Li, Xianzhong Chen
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Biotechnology for Biofuels and Bioproducts
Subjects:
Candida tropicalis
α-Humulene
Rate-limiting enzymes
Metabolic engineering
Mevalonate pathway
Online Access:https://doi.org/10.1186/s13068-022-02160-8

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