Antibacterial, Histochemical and Phytochemical Screening and Cytotoxicity Activity of Tubog, Ficus nota (Blanco) Merr Leaf and Fruit Extracts

Tubog, Ficus nota (Blanco) Merr a rare tree in the Philippines and was found in Barangay Tambis, Barobo, Surigao del Sur. The present study designed to evaluate the antibacterial activities of Tubog,Ficus nota (Blanco) Merr fruit and leaves with ethanolic extracts. Preliminary phytochemical and hist...

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Main Author: Levitah C. Mapatac
Format: Article
Language:English
Published: Center for Policy, Research and Development Studies 2015-12-01
Series:Recoletos Multidisciplinary Research Journal
Subjects:
Online Access:https://rmrj.usjr.edu.ph/rmrj/index.php/RMRJ/article/view/107
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author Levitah C. Mapatac
author_facet Levitah C. Mapatac
author_sort Levitah C. Mapatac
collection DOAJ
description Tubog, Ficus nota (Blanco) Merr a rare tree in the Philippines and was found in Barangay Tambis, Barobo, Surigao del Sur. The present study designed to evaluate the antibacterial activities of Tubog,Ficus nota (Blanco) Merr fruit and leaves with ethanolic extracts. Preliminary phytochemical and histochemical studies were carried out. The antimicrobial activity of the fruit extract against pathogenic strains evaluated based on the zone of inhibition using paper disc diffusion method with tested bacteria of Escherichia coli ATTC 25922, Staphylococcus aureus ATTC 25923, Klebsiella pneumonia UPCC 1360, and Salmonella typhimurium UPCC 1368.The qualitative phytochemical tests exhibited the presence of common bioactive compounds including alkaloids, tannins, flavonoids, saponins, flavonoids and anthraquinones. The aqueous extract has shown high activity in ethanolic extract has shown significantly good activity when compared to standard chemotherapeutic agent Chloramphenicol. Based on the result it was concluded that Ficus nota are rich in bioactive components and exhibits antimicrobial activity against pathogens. Cytotoxicity result showed higher toxicity with the fruit compared with ficus nota leaves ethanolic extract.
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spelling doaj.art-fbc7dc27d2ea4747a02549fcb9d5aa822022-12-21T18:59:29ZengCenter for Policy, Research and Development StudiesRecoletos Multidisciplinary Research Journal2423-13982408-37552015-12-0132https://doi.org/10.32871/rmrj1503.02.09Antibacterial, Histochemical and Phytochemical Screening and Cytotoxicity Activity of Tubog, Ficus nota (Blanco) Merr Leaf and Fruit ExtractsLevitah C. Mapatac0Caraga State UniversityTubog, Ficus nota (Blanco) Merr a rare tree in the Philippines and was found in Barangay Tambis, Barobo, Surigao del Sur. The present study designed to evaluate the antibacterial activities of Tubog,Ficus nota (Blanco) Merr fruit and leaves with ethanolic extracts. Preliminary phytochemical and histochemical studies were carried out. The antimicrobial activity of the fruit extract against pathogenic strains evaluated based on the zone of inhibition using paper disc diffusion method with tested bacteria of Escherichia coli ATTC 25922, Staphylococcus aureus ATTC 25923, Klebsiella pneumonia UPCC 1360, and Salmonella typhimurium UPCC 1368.The qualitative phytochemical tests exhibited the presence of common bioactive compounds including alkaloids, tannins, flavonoids, saponins, flavonoids and anthraquinones. The aqueous extract has shown high activity in ethanolic extract has shown significantly good activity when compared to standard chemotherapeutic agent Chloramphenicol. Based on the result it was concluded that Ficus nota are rich in bioactive components and exhibits antimicrobial activity against pathogens. Cytotoxicity result showed higher toxicity with the fruit compared with ficus nota leaves ethanolic extract.https://rmrj.usjr.edu.ph/rmrj/index.php/RMRJ/article/view/107ficus notaphytochemical screeningcytotoxicity and histochemical test
spellingShingle Levitah C. Mapatac
Antibacterial, Histochemical and Phytochemical Screening and Cytotoxicity Activity of Tubog, Ficus nota (Blanco) Merr Leaf and Fruit Extracts
Recoletos Multidisciplinary Research Journal
ficus nota
phytochemical screening
cytotoxicity and histochemical test
title Antibacterial, Histochemical and Phytochemical Screening and Cytotoxicity Activity of Tubog, Ficus nota (Blanco) Merr Leaf and Fruit Extracts
title_full Antibacterial, Histochemical and Phytochemical Screening and Cytotoxicity Activity of Tubog, Ficus nota (Blanco) Merr Leaf and Fruit Extracts
title_fullStr Antibacterial, Histochemical and Phytochemical Screening and Cytotoxicity Activity of Tubog, Ficus nota (Blanco) Merr Leaf and Fruit Extracts
title_full_unstemmed Antibacterial, Histochemical and Phytochemical Screening and Cytotoxicity Activity of Tubog, Ficus nota (Blanco) Merr Leaf and Fruit Extracts
title_short Antibacterial, Histochemical and Phytochemical Screening and Cytotoxicity Activity of Tubog, Ficus nota (Blanco) Merr Leaf and Fruit Extracts
title_sort antibacterial histochemical and phytochemical screening and cytotoxicity activity of tubog ficus nota blanco merr leaf and fruit extracts
topic ficus nota
phytochemical screening
cytotoxicity and histochemical test
url https://rmrj.usjr.edu.ph/rmrj/index.php/RMRJ/article/view/107
work_keys_str_mv AT levitahcmapatac antibacterialhistochemicalandphytochemicalscreeningandcytotoxicityactivityoftubogficusnotablancomerrleafandfruitextracts