Myeloid differentiation factor 88 (MyD88)-deficiency increases risk of diabetes in mice.
BACKGROUND: Multiple lines of evidence suggest innate immune response pathways to be involved in the development of obesity-associated diabetes although the molecular mechanism underling the disease is unknown. Recent observations suggest that saturated fatty acids can act as a ligand for toll-like...
Main Authors: | Toru Hosoi, Shota Yokoyama, Suguru Matsuo, Shizuo Akira, Koichiro Ozawa |
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Format: | Article |
Jezik: | English |
Izdano: |
Public Library of Science (PLoS)
2010-01-01
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Serija: | PLoS ONE |
Online dostop: | http://europepmc.org/articles/PMC2932727?pdf=render |
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