The Wnt Target Gene L1 in Colon Cancer Invasion and Metastasis

The Wnt-β-catenin signaling pathway is highly conserved during evolution and determines normal tissue homeostasis. Hyperactivation of Wnt-β-catenin signaling is a characteristic feature of colorectal cancer (CRC) development. β-catenin is a major transducer of the Wnt signal from the cytoplasm into...

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Bibliographic Details
Main Authors: Gal Haase, Nancy Gavert, Thomas Brabletz, Avri Ben-Ze’ev
Format: Article
Language:English
Published: MDPI AG 2016-05-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/8/5/48