The Wnt Target Gene L1 in Colon Cancer Invasion and Metastasis
The Wnt-β-catenin signaling pathway is highly conserved during evolution and determines normal tissue homeostasis. Hyperactivation of Wnt-β-catenin signaling is a characteristic feature of colorectal cancer (CRC) development. β-catenin is a major transducer of the Wnt signal from the cytoplasm into...
Main Authors: | Gal Haase, Nancy Gavert, Thomas Brabletz, Avri Ben-Ze’ev |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2016-05-01
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Series: | Cancers |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6694/8/5/48 |
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