Simplified regimen of combined low-dose rituximab for autoimmune encephalitis with neuronal surface antibodies

Simplified regimen of combined low-dose rituximab for autoimmune encephalitis with neuronal surface antibodies

Abstract Background Autoimmune encephalitis (AE) with neuronal surface antibodies (NSAbs) presents pathogenesis mediated by B cell-secreting antibodies. Rituximab is a second-line choice for the treatment for AE with NSAbs, which can cause B cell depletion via targeting CD20. However, the optimal pr...

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Bibliographic Details
Main Authors: Ying Du, Chao Zhao, Juntong Liu, Chuan Li, Qi Yan, Lin Li, Yunfeng Hao, Dan Yao, Huaxing Si, Yingjun Zhao, Wei Zhang
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Journal of Neuroinflammation
Subjects:
Autoimmune encephalitis
Neuronal surface antibody
Rituximab
Low dose
Combined treatment
Clinical outcome
Online Access:https://doi.org/10.1186/s12974-022-02622-8

Internet

https://doi.org/10.1186/s12974-022-02622-8

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