Lyophilized allogeneic costal cartilage graft for septorhinoplasty
Background As rhinoplasty techniques have become more complex, surgeons often need more than what septal or conchal cartilage can provide. While costal cartilage became more popular for that reason, some surgeons are still uncomfortable with its invasiveness and donor site morbidity. Here, we used l...
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| Format: | Article |
| Language: | English |
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Korean Society for Aesthetic Plastic Surgery
2023-10-01
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| Series: | Archives of Aesthetic Plastic Surgery |
| Subjects: | |
| Online Access: | http://e-aaps.org/upload/pdf/aaps-2023-00808.pdf |
| _version_ | 1797635307337678848 |
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| author | Jin Sup Eom Dong Jin Kim Jin Woo Song Jong Woo Choi Kyung Suck Koh |
| author_facet | Jin Sup Eom Dong Jin Kim Jin Woo Song Jong Woo Choi Kyung Suck Koh |
| author_sort | Jin Sup Eom |
| collection | DOAJ |
| description | Background As rhinoplasty techniques have become more complex, surgeons often need more than what septal or conchal cartilage can provide. While costal cartilage became more popular for that reason, some surgeons are still uncomfortable with its invasiveness and donor site morbidity. Here, we used lyophilized allogeneic costal cartilage for septorhinoplasty and investigated its safety and usefulness. Methods The costal cartilage was harvested from a cadaveric donor and treated via multiple steps, including defatting and lyophilization, to remove all viable cells and antigenicity. The cartilage was then stored at room temperature and rehydrated 24 hours before use. Lyophilized cartilage allografts were used in 20 patients. Three types of septal graft were performed — spreader, batten, and extension — to correct septal or columellar deviation and enhance the nasal tip. Results The mean follow-up period was 4.3 years. In all cases, the graft successfully met the rhinoplasty purpose. No significant deformation was detected in any of the patients. Although warping was observed in one patient (5%), there was no case of clinical infection, extrusion, or graft removal and no revisional surgery for an unfavorable aesthetic result. Conclusions Lyophilized allogeneic cartilage was used for septorhinoplasty very safely and effectively. It can be carved into any shape and has all other properties required for perfectly replacing autologous costal cartilage. The main advantage of cartilage allografts is a limitless supply of high-quality cartilage without donor site morbidity. The disadvantages include the need for special facilities and manpower and extra covering cost. |
| first_indexed | 2024-03-11T12:20:22Z |
| format | Article |
| id | doaj.art-fbe05addccb24bf696e33d9f6ba1bb4e |
| institution | Directory Open Access Journal |
| issn | 2234-0831 2288-9337 |
| language | English |
| last_indexed | 2024-03-11T12:20:22Z |
| publishDate | 2023-10-01 |
| publisher | Korean Society for Aesthetic Plastic Surgery |
| record_format | Article |
| series | Archives of Aesthetic Plastic Surgery |
| spelling | doaj.art-fbe05addccb24bf696e33d9f6ba1bb4e2023-11-07T05:11:36ZengKorean Society for Aesthetic Plastic SurgeryArchives of Aesthetic Plastic Surgery2234-08312288-93372023-10-0129419019410.14730/aaps.2023.00808820Lyophilized allogeneic costal cartilage graft for septorhinoplastyJin Sup Eom0Dong Jin Kim1Jin Woo Song2Jong Woo Choi3Kyung Suck Koh4 Department of Plastic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea Department of Plastic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea Dareum Plastic Surgery, Seoul, Korea Department of Plastic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea Onul Plastic Surgery, Seoul, KoreaBackground As rhinoplasty techniques have become more complex, surgeons often need more than what septal or conchal cartilage can provide. While costal cartilage became more popular for that reason, some surgeons are still uncomfortable with its invasiveness and donor site morbidity. Here, we used lyophilized allogeneic costal cartilage for septorhinoplasty and investigated its safety and usefulness. Methods The costal cartilage was harvested from a cadaveric donor and treated via multiple steps, including defatting and lyophilization, to remove all viable cells and antigenicity. The cartilage was then stored at room temperature and rehydrated 24 hours before use. Lyophilized cartilage allografts were used in 20 patients. Three types of septal graft were performed — spreader, batten, and extension — to correct septal or columellar deviation and enhance the nasal tip. Results The mean follow-up period was 4.3 years. In all cases, the graft successfully met the rhinoplasty purpose. No significant deformation was detected in any of the patients. Although warping was observed in one patient (5%), there was no case of clinical infection, extrusion, or graft removal and no revisional surgery for an unfavorable aesthetic result. Conclusions Lyophilized allogeneic cartilage was used for septorhinoplasty very safely and effectively. It can be carved into any shape and has all other properties required for perfectly replacing autologous costal cartilage. The main advantage of cartilage allografts is a limitless supply of high-quality cartilage without donor site morbidity. The disadvantages include the need for special facilities and manpower and extra covering cost.http://e-aaps.org/upload/pdf/aaps-2023-00808.pdfrhinoplastyallograftscartilagefreeze drying |
| spellingShingle | Jin Sup Eom Dong Jin Kim Jin Woo Song Jong Woo Choi Kyung Suck Koh Lyophilized allogeneic costal cartilage graft for septorhinoplasty Archives of Aesthetic Plastic Surgery rhinoplasty allografts cartilage freeze drying |
| title | Lyophilized allogeneic costal cartilage graft for septorhinoplasty |
| title_full | Lyophilized allogeneic costal cartilage graft for septorhinoplasty |
| title_fullStr | Lyophilized allogeneic costal cartilage graft for septorhinoplasty |
| title_full_unstemmed | Lyophilized allogeneic costal cartilage graft for septorhinoplasty |
| title_short | Lyophilized allogeneic costal cartilage graft for septorhinoplasty |
| title_sort | lyophilized allogeneic costal cartilage graft for septorhinoplasty |
| topic | rhinoplasty allografts cartilage freeze drying |
| url | http://e-aaps.org/upload/pdf/aaps-2023-00808.pdf |
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