Genome-Scale CRISPR Knockout Screening Identifies BACH1 as a Key Regulator of Aflatoxin B<sub>1</sub>-Induced Oxidative Damage

Genome-Scale CRISPR Knockout Screening Identifies BACH1 as a Key Regulator of Aflatoxin B<sub>1</sub>-Induced Oxidative Damage

Aflatoxin B<sub>1</sub> (AFB<sub>1</sub>) is amongst the mycotoxins commonly affecting human and animal health, raising global food safety and control concerns. The mechanisms underlying AFB<sub>1</sub> toxicity are poorly understood. Moreover, antidotes against A...

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Bibliographic Details
Main Authors: Jinfu Zhang, Siyi Hu, Changzhi Zhao, Yuan Zhou, Lu Zhang, Hailong Liu, Peng Zhou, Sheng Li, Liangliang Fu, Zhuqing Zheng, Yue Xiang, Xuewen Xu, Jinxue Ruan, Xinyun Li, Lvhui Sun, Gang Cao, Shuhong Zhao, Xu Wang, Shengsong Xie
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Antioxidants
Subjects:
AFB<sub>1</sub>
BACH1
CRISPR screening
inhibitor
Online Access:https://www.mdpi.com/2076-3921/11/9/1787

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