Involvement of the Spinal Serotonergic System in the Analgesic Effect of [6]-Shogaol in Oxaliplatin-Induced Neuropathic Pain in Mice
Oxaliplatin is a chemotherapy drug that can induce severe acute neuropathy in patients within hours of treatment. In our previous study, 10 mg/kg [6]-shogaol (i.p.) significantly alleviated cold and mechanical allodynia induced by a 6 mg/kg oxaliplatin injection (i.p.); however, the precise serotoni...
Main Authors: | Juan Gang, Keun-Tae Park, Suyong Kim, Woojin Kim |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-10-01
|
Series: | Pharmaceuticals |
Subjects: | |
Online Access: | https://www.mdpi.com/1424-8247/16/10/1465 |
Similar Items
-
[6]-Shogaol Attenuates Oxaliplatin-Induced Allodynia through Serotonergic Receptors and GABA in the Spinal Cord in Mice
by: Suyong Kim, et al.
Published: (2022-06-01) -
Involvement of Serotonergic System in Oxaliplatin-Induced Neuropathic Pain
by: Ji Hwan Lee, et al.
Published: (2021-08-01) -
Red Ginger Extract Prevents the Development of Oxaliplatin-Induced Neuropathic Pain by Inhibiting the Spinal Noradrenergic System in Mice
by: Keun-Tae Park, et al.
Published: (2023-02-01) -
<i>Zingiber officinale</i> Roscoe Rhizomes Attenuate Oxaliplatin-Induced Neuropathic Pain in Mice
by: Ji Hwan Lee, et al.
Published: (2021-01-01) -
Anti-inflammatory effect and signaling mechanism of 8-shogaol and 10-shogaol in a dextran sodium sulfate-induced colitis mouse model
by: Ha-Rim Kim, et al.
Published: (2023-01-01)