CCL2 as an Important Mediator of Prostate Cancer Growth In Vivo through the Regulation of Macrophage Infiltration
The ability of CCL2 to influence prostate cancer tumorigenesis and metastasis may occur through two distinct mechanisms: 1) a direct effect on tumor cell growth and function, and 2) an indirect effect on the tumor microenvironment by the regulation of macrophage mobilization and infiltration into th...
Main Authors: | Robert D. Loberg, Chi Ying, Matt Craig, Li Yan, Linda A. Snyder, Kenneth J. Pienta |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2007-07-01
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Series: | Neoplasia: An International Journal for Oncology Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558607800807 |
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