Effect of different grade of primary hypertension on corneal endothelial cells

AIM:To investigate the effect of different stage of primary hypertension on corneal endothelial cells by Specular Microscope. <p>METHODS:Case-control study was taken. The case group included 71 patients(142 eyes)diagnosed with primary hypertension, including 22 patients(44 eyes)in group stage...

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Main Author: Lin Wang
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2015-12-01
Series:Guoji Yanke Zazhi
Subjects:
Online Access:http://ies.ijo.cn/cn_publish/2015/12/201512031.pdf
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author Lin Wang
author_facet Lin Wang
author_sort Lin Wang
collection DOAJ
description AIM:To investigate the effect of different stage of primary hypertension on corneal endothelial cells by Specular Microscope. <p>METHODS:Case-control study was taken. The case group included 71 patients(142 eyes)diagnosed with primary hypertension, including 22 patients(44 eyes)in group stage 1, 23 patients(46 eyes)in group stage 2 and 26 patients(52 eyes)in group stage 3. The control group included 69 healthy subjects(138 eyes). There was no statistical differences in gender and age(<i>P</i>>0.05), and no systemic or eye disease for the both groups.Statistical analysis was made on the corneal endothelial cells including average cell area, average cell density, coefficient of variation and percentage of hexagonal cells. <p>RESULTS:Average cell area and average cell density had no statistical differences for both groups. Coefficient of variation increased(<i>t</i>=3.34, <i>P</i><0.05)and percentage of hexagonal cells decreased(<i>t</i>=-2.07, <i>P</i><0.05)for case group. There was no significant difference on average cell area and average cell density among the three subgroups in case group(<i>P</i>>0.05). There was significant differences for coefficient of variation and percentage of hexagonal cells(<i>P</i> <0.05)among the three subgroups.. <p>CONCLUSION:Compared with the control group, corneal endothelial cells of patients with primary hypertension increases significantly on coefficient of variation and decreases on percentage of hexagonal cells. Patients with different hypertension grades have different coefficient of variation and percentage of hexagonal cells.
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spelling doaj.art-fbe6017587b746c2a55d039b64fe94822022-12-22T02:52:40ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232015-12-0115122140214210.3980/j.issn.1672-5123.2015.12.31Effect of different grade of primary hypertension on corneal endothelial cellsLin Wang0Department of Ophthalmology,Shenyang the Fourth Hospital of People, Shenyang 110031, Liaoning Province, ChinaAIM:To investigate the effect of different stage of primary hypertension on corneal endothelial cells by Specular Microscope. <p>METHODS:Case-control study was taken. The case group included 71 patients(142 eyes)diagnosed with primary hypertension, including 22 patients(44 eyes)in group stage 1, 23 patients(46 eyes)in group stage 2 and 26 patients(52 eyes)in group stage 3. The control group included 69 healthy subjects(138 eyes). There was no statistical differences in gender and age(<i>P</i>>0.05), and no systemic or eye disease for the both groups.Statistical analysis was made on the corneal endothelial cells including average cell area, average cell density, coefficient of variation and percentage of hexagonal cells. <p>RESULTS:Average cell area and average cell density had no statistical differences for both groups. Coefficient of variation increased(<i>t</i>=3.34, <i>P</i><0.05)and percentage of hexagonal cells decreased(<i>t</i>=-2.07, <i>P</i><0.05)for case group. There was no significant difference on average cell area and average cell density among the three subgroups in case group(<i>P</i>>0.05). There was significant differences for coefficient of variation and percentage of hexagonal cells(<i>P</i> <0.05)among the three subgroups.. <p>CONCLUSION:Compared with the control group, corneal endothelial cells of patients with primary hypertension increases significantly on coefficient of variation and decreases on percentage of hexagonal cells. Patients with different hypertension grades have different coefficient of variation and percentage of hexagonal cells.http://ies.ijo.cn/cn_publish/2015/12/201512031.pdfprimary hypertensioncorneaendothelial cell
spellingShingle Lin Wang
Effect of different grade of primary hypertension on corneal endothelial cells
Guoji Yanke Zazhi
primary hypertension
cornea
endothelial cell
title Effect of different grade of primary hypertension on corneal endothelial cells
title_full Effect of different grade of primary hypertension on corneal endothelial cells
title_fullStr Effect of different grade of primary hypertension on corneal endothelial cells
title_full_unstemmed Effect of different grade of primary hypertension on corneal endothelial cells
title_short Effect of different grade of primary hypertension on corneal endothelial cells
title_sort effect of different grade of primary hypertension on corneal endothelial cells
topic primary hypertension
cornea
endothelial cell
url http://ies.ijo.cn/cn_publish/2015/12/201512031.pdf
work_keys_str_mv AT linwang effectofdifferentgradeofprimaryhypertensiononcornealendothelialcells