Effect of different grade of primary hypertension on corneal endothelial cells
AIM:To investigate the effect of different stage of primary hypertension on corneal endothelial cells by Specular Microscope. <p>METHODS:Case-control study was taken. The case group included 71 patients(142 eyes)diagnosed with primary hypertension, including 22 patients(44 eyes)in group stage...
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Format: | Article |
Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2015-12-01
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Series: | Guoji Yanke Zazhi |
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Online Access: | http://ies.ijo.cn/cn_publish/2015/12/201512031.pdf |
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author | Lin Wang |
author_facet | Lin Wang |
author_sort | Lin Wang |
collection | DOAJ |
description | AIM:To investigate the effect of different stage of primary hypertension on corneal endothelial cells by Specular Microscope. <p>METHODS:Case-control study was taken. The case group included 71 patients(142 eyes)diagnosed with primary hypertension, including 22 patients(44 eyes)in group stage 1, 23 patients(46 eyes)in group stage 2 and 26 patients(52 eyes)in group stage 3. The control group included 69 healthy subjects(138 eyes). There was no statistical differences in gender and age(<i>P</i>>0.05), and no systemic or eye disease for the both groups.Statistical analysis was made on the corneal endothelial cells including average cell area, average cell density, coefficient of variation and percentage of hexagonal cells. <p>RESULTS:Average cell area and average cell density had no statistical differences for both groups. Coefficient of variation increased(<i>t</i>=3.34, <i>P</i><0.05)and percentage of hexagonal cells decreased(<i>t</i>=-2.07, <i>P</i><0.05)for case group. There was no significant difference on average cell area and average cell density among the three subgroups in case group(<i>P</i>>0.05). There was significant differences for coefficient of variation and percentage of hexagonal cells(<i>P</i> <0.05)among the three subgroups.. <p>CONCLUSION:Compared with the control group, corneal endothelial cells of patients with primary hypertension increases significantly on coefficient of variation and decreases on percentage of hexagonal cells. Patients with different hypertension grades have different coefficient of variation and percentage of hexagonal cells. |
first_indexed | 2024-04-13T09:19:30Z |
format | Article |
id | doaj.art-fbe6017587b746c2a55d039b64fe9482 |
institution | Directory Open Access Journal |
issn | 1672-5123 1672-5123 |
language | English |
last_indexed | 2024-04-13T09:19:30Z |
publishDate | 2015-12-01 |
publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
record_format | Article |
series | Guoji Yanke Zazhi |
spelling | doaj.art-fbe6017587b746c2a55d039b64fe94822022-12-22T02:52:40ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232015-12-0115122140214210.3980/j.issn.1672-5123.2015.12.31Effect of different grade of primary hypertension on corneal endothelial cellsLin Wang0Department of Ophthalmology,Shenyang the Fourth Hospital of People, Shenyang 110031, Liaoning Province, ChinaAIM:To investigate the effect of different stage of primary hypertension on corneal endothelial cells by Specular Microscope. <p>METHODS:Case-control study was taken. The case group included 71 patients(142 eyes)diagnosed with primary hypertension, including 22 patients(44 eyes)in group stage 1, 23 patients(46 eyes)in group stage 2 and 26 patients(52 eyes)in group stage 3. The control group included 69 healthy subjects(138 eyes). There was no statistical differences in gender and age(<i>P</i>>0.05), and no systemic or eye disease for the both groups.Statistical analysis was made on the corneal endothelial cells including average cell area, average cell density, coefficient of variation and percentage of hexagonal cells. <p>RESULTS:Average cell area and average cell density had no statistical differences for both groups. Coefficient of variation increased(<i>t</i>=3.34, <i>P</i><0.05)and percentage of hexagonal cells decreased(<i>t</i>=-2.07, <i>P</i><0.05)for case group. There was no significant difference on average cell area and average cell density among the three subgroups in case group(<i>P</i>>0.05). There was significant differences for coefficient of variation and percentage of hexagonal cells(<i>P</i> <0.05)among the three subgroups.. <p>CONCLUSION:Compared with the control group, corneal endothelial cells of patients with primary hypertension increases significantly on coefficient of variation and decreases on percentage of hexagonal cells. Patients with different hypertension grades have different coefficient of variation and percentage of hexagonal cells.http://ies.ijo.cn/cn_publish/2015/12/201512031.pdfprimary hypertensioncorneaendothelial cell |
spellingShingle | Lin Wang Effect of different grade of primary hypertension on corneal endothelial cells Guoji Yanke Zazhi primary hypertension cornea endothelial cell |
title | Effect of different grade of primary hypertension on corneal endothelial cells |
title_full | Effect of different grade of primary hypertension on corneal endothelial cells |
title_fullStr | Effect of different grade of primary hypertension on corneal endothelial cells |
title_full_unstemmed | Effect of different grade of primary hypertension on corneal endothelial cells |
title_short | Effect of different grade of primary hypertension on corneal endothelial cells |
title_sort | effect of different grade of primary hypertension on corneal endothelial cells |
topic | primary hypertension cornea endothelial cell |
url | http://ies.ijo.cn/cn_publish/2015/12/201512031.pdf |
work_keys_str_mv | AT linwang effectofdifferentgradeofprimaryhypertensiononcornealendothelialcells |