Modulation of occluding junctions alters the hematopoietic niche to trigger immune activation

Stem cells are regulated by signals from their microenvironment, or niche. During Drosophila hematopoiesis, a niche regulates prohemocytes to control hemocyte production. Immune challenges activate cell-signalling to initiate the cellular and innate immune response. Specifically, certain immune chal...

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Bibliographic Details
Main Authors: Rohan J Khadilkar, Wayne Vogl, Katharine Goodwin, Guy Tanentzapf
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-08-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/28081