Constitutive activation of ectodermal β-catenin induces ectopic outgrowths at various positions in mouse embryo and affects abdominal ventral body wall closure.

Constitutive activation of ectodermal β-catenin induces ectopic outgrowths at various positions in mouse embryo and affects abdominal ventral body wall closure.

Vertebrate limbs originate from the lateral plate mesoderm (LPM) and the overlying ectoderm. While normal limb formation in defined regions has been well studied, the question of whether other positions retain limb-forming potential has not been fully investigated in mice. By ectopically activating...

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Bibliographic Details
Main Authors: Xuming Zhu, Sixia Huang, Lingling Zhang, Yumei Wu, Yingwei Chen, Yixin Tao, Yushu Wang, Shigang He, Sanbing Shen, Ji Wu, Baojie Li, Xizhi Guo, Lin He, Gang Ma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3960177?pdf=render

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