On rare variants in principal component analysis of population stratification
Abstract Background Population stratification is a known confounder of genome-wide association studies, as it can lead to false positive results. Principal component analysis (PCA) method is widely applied in the analysis of population structure with common variants. However, it is still unclear abo...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2020-03-01
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| Series: | BMC Genetics |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12863-020-0833-x |