Albumin tailoring fluorescence and photothermal conversion effect of near-infrared-II fluorophore with aggregation-induced emission characteristics
There is a balance between the fluorescence and photothermal properties of fluorescent molecules. Here, the authors report on an NIR-II fluorophore which binds with human serum albumin changing the equilibrium, increasing the photothermal efficiency, and demonstrate application of this for tumour ab...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2019-05-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-019-10056-9 |
| _version_ | 1818405722285670400 |
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| author | Shuai Gao Guoguang Wei Sihang Zhang Binbin Zheng Jiaojiao Xu Gaoxian Chen Mingwang Li Shaoli Song Wei Fu Zeyu Xiao Wei Lu |
| author_facet | Shuai Gao Guoguang Wei Sihang Zhang Binbin Zheng Jiaojiao Xu Gaoxian Chen Mingwang Li Shaoli Song Wei Fu Zeyu Xiao Wei Lu |
| author_sort | Shuai Gao |
| collection | DOAJ |
| description | There is a balance between the fluorescence and photothermal properties of fluorescent molecules. Here, the authors report on an NIR-II fluorophore which binds with human serum albumin changing the equilibrium, increasing the photothermal efficiency, and demonstrate application of this for tumour ablation. |
| first_indexed | 2024-12-14T09:00:34Z |
| format | Article |
| id | doaj.art-fbf0642c74034a9fb10ec9be72017b09 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-14T09:00:34Z |
| publishDate | 2019-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-fbf0642c74034a9fb10ec9be72017b092022-12-21T23:08:49ZengNature PortfolioNature Communications2041-17232019-05-0110111510.1038/s41467-019-10056-9Albumin tailoring fluorescence and photothermal conversion effect of near-infrared-II fluorophore with aggregation-induced emission characteristicsShuai Gao0Guoguang Wei1Sihang Zhang2Binbin Zheng3Jiaojiao Xu4Gaoxian Chen5Mingwang Li6Shaoli Song7Wei Fu8Zeyu Xiao9Wei Lu10Key Laboratory of Smart Drug Delivery, Ministry of Education, & State Key Laboratory of Molecular Engineering of Polymers, School of Pharmacy & Minhang Hospital, Fudan UniversityKey Laboratory of Smart Drug Delivery, Ministry of Education, & State Key Laboratory of Molecular Engineering of Polymers, School of Pharmacy & Minhang Hospital, Fudan UniversityKey Laboratory of Smart Drug Delivery, Ministry of Education, & State Key Laboratory of Molecular Engineering of Polymers, School of Pharmacy & Minhang Hospital, Fudan UniversityKey Laboratory of Smart Drug Delivery, Ministry of Education, & State Key Laboratory of Molecular Engineering of Polymers, School of Pharmacy & Minhang Hospital, Fudan UniversityKey Laboratory of Smart Drug Delivery, Ministry of Education, & State Key Laboratory of Molecular Engineering of Polymers, School of Pharmacy & Minhang Hospital, Fudan UniversityInstitute of Molecular Medicine, Clinical and Fundamental Research Center, Renji Hospital, & Department of Pharmacology and Chemical Biology, Shanghai Jiao Tong University School of MedicineInstitute of Molecular Medicine, Clinical and Fundamental Research Center, Renji Hospital, & Department of Pharmacology and Chemical Biology, Shanghai Jiao Tong University School of MedicineDepartment of Nuclear Medicine, Shanghai Cancer Center, Fudan UniversityKey Laboratory of Smart Drug Delivery, Ministry of Education, & State Key Laboratory of Molecular Engineering of Polymers, School of Pharmacy & Minhang Hospital, Fudan UniversityInstitute of Molecular Medicine, Clinical and Fundamental Research Center, Renji Hospital, & Department of Pharmacology and Chemical Biology, Shanghai Jiao Tong University School of MedicineKey Laboratory of Smart Drug Delivery, Ministry of Education, & State Key Laboratory of Molecular Engineering of Polymers, School of Pharmacy & Minhang Hospital, Fudan UniversityThere is a balance between the fluorescence and photothermal properties of fluorescent molecules. Here, the authors report on an NIR-II fluorophore which binds with human serum albumin changing the equilibrium, increasing the photothermal efficiency, and demonstrate application of this for tumour ablation.https://doi.org/10.1038/s41467-019-10056-9 |
| spellingShingle | Shuai Gao Guoguang Wei Sihang Zhang Binbin Zheng Jiaojiao Xu Gaoxian Chen Mingwang Li Shaoli Song Wei Fu Zeyu Xiao Wei Lu Albumin tailoring fluorescence and photothermal conversion effect of near-infrared-II fluorophore with aggregation-induced emission characteristics Nature Communications |
| title | Albumin tailoring fluorescence and photothermal conversion effect of near-infrared-II fluorophore with aggregation-induced emission characteristics |
| title_full | Albumin tailoring fluorescence and photothermal conversion effect of near-infrared-II fluorophore with aggregation-induced emission characteristics |
| title_fullStr | Albumin tailoring fluorescence and photothermal conversion effect of near-infrared-II fluorophore with aggregation-induced emission characteristics |
| title_full_unstemmed | Albumin tailoring fluorescence and photothermal conversion effect of near-infrared-II fluorophore with aggregation-induced emission characteristics |
| title_short | Albumin tailoring fluorescence and photothermal conversion effect of near-infrared-II fluorophore with aggregation-induced emission characteristics |
| title_sort | albumin tailoring fluorescence and photothermal conversion effect of near infrared ii fluorophore with aggregation induced emission characteristics |
| url | https://doi.org/10.1038/s41467-019-10056-9 |
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