Inferring a spatial code of cell-cell interactions across a whole animal body.

Cell-cell interactions shape cellular function and ultimately organismal phenotype. Interacting cells can sense their mutual distance using combinations of ligand-receptor pairs, suggesting the existence of a spatial code, i.e., signals encoding spatial properties of cellular organization. However,...

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Bibliographic Details
Main Authors: Erick Armingol, Abbas Ghaddar, Chintan J Joshi, Hratch Baghdassarian, Isaac Shamie, Jason Chan, Hsuan-Lin Her, Samuel Berhanu, Anushka Dar, Fabiola Rodriguez-Armstrong, Olivia Yang, Eyleen J O'Rourke, Nathan E Lewis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-11-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1010715