The role of serum lipid profile in the pathogenesis of arterial hypertension

Hypertension is a key contributor to the high global burden of cardiovascular morbidity and mortality, due to its increasing prevalence worldwide. In clinical practice, dyslipidemia and hypertension often coexist, possibly because they share similar underlying causes, such as endothelial dysfunction...

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Main Authors: Rafaqat Saira, Rafaqat Sana, Klisić Aleksandra
Format: Article
Language:srp
Published: Pharmaceutical Association of Serbia, Belgrade, Serbia 2024-01-01
Series:Arhiv za farmaciju
Subjects:
Online Access:https://scindeks-clanci.ceon.rs/data/pdf/0004-1963/2024/0004-19632401076R.pdf
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author Rafaqat Saira
Rafaqat Sana
Klisić Aleksandra
author_facet Rafaqat Saira
Rafaqat Sana
Klisić Aleksandra
author_sort Rafaqat Saira
collection DOAJ
description Hypertension is a key contributor to the high global burden of cardiovascular morbidity and mortality, due to its increasing prevalence worldwide. In clinical practice, dyslipidemia and hypertension often coexist, possibly because they share similar underlying causes, such as endothelial dysfunction and obesity. Consequently, this review article presents the collective findings on the role of lipid profile parameters in arterial hypertension. Individuals with hypertension often have significantly higher mean serum levels of triglycerides (TG), total cholesterol (TC), and low-density lipoprotein cholesterol (LDL-C), while exhibiting lower mean serum levels of high-density lipoprotein cholesterol (HDL-C) compared to those without hypertension. TC and HDL-C play an important role in the pathogenesis of arterial hypertension. However, there is a lack of studies explaining the link between TG and LDL-C and arterial hypertension. Future studies are necessary to fully elucidate the exact mechanisms by which the mentioned lipid parameters contribute to arterial hypertension.
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spelling doaj.art-fbf3b364bff54d16a3ceae63b2668a6c2024-04-04T08:11:07ZsrpPharmaceutical Association of Serbia, Belgrade, SerbiaArhiv za farmaciju0004-19632217-87672024-01-01741769110.5937/arhfarm74-479080004-19632401076RThe role of serum lipid profile in the pathogenesis of arterial hypertensionRafaqat Saira0Rafaqat Sana1Klisić Aleksandra2https://orcid.org/0000-0001-7870-0996Lahore College for Women University, Department of Zoology (Molecular Physiology), Lahore, Punjab, PakistanLahore College for Women University, Department of Biotechnology (Human Genetics), Lahore, Punjab, PakistanUniversity of Montenegro, Faculty of Medicine, Podgorica, MontenegroHypertension is a key contributor to the high global burden of cardiovascular morbidity and mortality, due to its increasing prevalence worldwide. In clinical practice, dyslipidemia and hypertension often coexist, possibly because they share similar underlying causes, such as endothelial dysfunction and obesity. Consequently, this review article presents the collective findings on the role of lipid profile parameters in arterial hypertension. Individuals with hypertension often have significantly higher mean serum levels of triglycerides (TG), total cholesterol (TC), and low-density lipoprotein cholesterol (LDL-C), while exhibiting lower mean serum levels of high-density lipoprotein cholesterol (HDL-C) compared to those without hypertension. TC and HDL-C play an important role in the pathogenesis of arterial hypertension. However, there is a lack of studies explaining the link between TG and LDL-C and arterial hypertension. Future studies are necessary to fully elucidate the exact mechanisms by which the mentioned lipid parameters contribute to arterial hypertension.https://scindeks-clanci.ceon.rs/data/pdf/0004-1963/2024/0004-19632401076R.pdfarterial hypertensionlipid profileatherosclerosis
spellingShingle Rafaqat Saira
Rafaqat Sana
Klisić Aleksandra
The role of serum lipid profile in the pathogenesis of arterial hypertension
Arhiv za farmaciju
arterial hypertension
lipid profile
atherosclerosis
title The role of serum lipid profile in the pathogenesis of arterial hypertension
title_full The role of serum lipid profile in the pathogenesis of arterial hypertension
title_fullStr The role of serum lipid profile in the pathogenesis of arterial hypertension
title_full_unstemmed The role of serum lipid profile in the pathogenesis of arterial hypertension
title_short The role of serum lipid profile in the pathogenesis of arterial hypertension
title_sort role of serum lipid profile in the pathogenesis of arterial hypertension
topic arterial hypertension
lipid profile
atherosclerosis
url https://scindeks-clanci.ceon.rs/data/pdf/0004-1963/2024/0004-19632401076R.pdf
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