Association between the incidence of type 1 diabetes mellitus and tuberculosis or bacillus Calmette-Guérin immunization in children and adolescents
Purpose The correlation between the incidence of type 1 diabetes mellitus (T1DM) and tuberculosis or bacillus Calmette-Guérin (BCG) vaccination rate in individuals aged <15 years was investigated using worldwide data. Methods The incidence of T1DM, rate of BCG vaccination, and incidence of tuberc...
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| Format: | Article |
| Language: | English |
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Korean Society of Pediatric Endocrinology
2023-12-01
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| Series: | Annals of Pediatric Endocrinology & Metabolism |
| Subjects: | |
| Online Access: | http://e-apem.org/upload/pdf/apem-2244254-127.pdf |
| _version_ | 1797375625101574144 |
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| author | Ji Young Park Young June Choe Yaeji Lim Hyunsung Kim Jaehyun Kim |
| author_facet | Ji Young Park Young June Choe Yaeji Lim Hyunsung Kim Jaehyun Kim |
| author_sort | Ji Young Park |
| collection | DOAJ |
| description | Purpose The correlation between the incidence of type 1 diabetes mellitus (T1DM) and tuberculosis or bacillus Calmette-Guérin (BCG) vaccination rate in individuals aged <15 years was investigated using worldwide data. Methods The incidence of T1DM, rate of BCG vaccination, and incidence of tuberculosis were obtained from the Diabetes Atlas 9th edition of the International Diabetes Federation and the Global Health Observatory data repository of the World Health Organization. Gross domestic product (GDP) per capita and population data by country were obtained from the World Bank and United Nations, respectively. Results GDP per capita negatively correlated with the incidence of tuberculosis and positively correlated with the incidence of T1DM (coefficient=-0.630 and 0.596, respectively; all P<0.001). The incidence of T1DM and tuberculosis was significantly associated with the Organisation for Economic Cooperation and Development (OECD) status (P<0.001). After adjusting for GDP per capita, regional grouping, and OECD status, the incidence of T1DM negatively correlated with that of tuberculosis (R2 =0.729, P=0.009). However, there was no association between the BCG vaccination rate and incidence of T1DM (P=0.890). Conclusions There was a negative correlation between the incidence of tuberculosis and T1DM in children and adolescents aged <15 years at the country level. |
| first_indexed | 2024-03-08T19:27:06Z |
| format | Article |
| id | doaj.art-fbf42ba69dd747e0a549860ed3afea3a |
| institution | Directory Open Access Journal |
| issn | 2287-1012 2287-1292 |
| language | English |
| last_indexed | 2024-03-08T19:27:06Z |
| publishDate | 2023-12-01 |
| publisher | Korean Society of Pediatric Endocrinology |
| record_format | Article |
| series | Annals of Pediatric Endocrinology & Metabolism |
| spelling | doaj.art-fbf42ba69dd747e0a549860ed3afea3a2023-12-26T08:34:09ZengKorean Society of Pediatric EndocrinologyAnnals of Pediatric Endocrinology & Metabolism2287-10122287-12922023-12-0128425125710.6065/apem.2244254.1271005Association between the incidence of type 1 diabetes mellitus and tuberculosis or bacillus Calmette-Guérin immunization in children and adolescentsJi Young Park0Young June Choe1Yaeji Lim2Hyunsung Kim3Jaehyun Kim4 Department of Pediatrics, Chung-Ang University Hospital, Seoul, Korea Department of Pediatrics, Korea University Anam Hospital, Seoul, Korea Department of Applied Statistics, Chung-Ang University, Seoul, Korea Department of Applied Statistics, Chung-Ang University, Seoul, Korea Department of Pediatrics, Seoul National University Bundang Hospital, Seongnam, KoreaPurpose The correlation between the incidence of type 1 diabetes mellitus (T1DM) and tuberculosis or bacillus Calmette-Guérin (BCG) vaccination rate in individuals aged <15 years was investigated using worldwide data. Methods The incidence of T1DM, rate of BCG vaccination, and incidence of tuberculosis were obtained from the Diabetes Atlas 9th edition of the International Diabetes Federation and the Global Health Observatory data repository of the World Health Organization. Gross domestic product (GDP) per capita and population data by country were obtained from the World Bank and United Nations, respectively. Results GDP per capita negatively correlated with the incidence of tuberculosis and positively correlated with the incidence of T1DM (coefficient=-0.630 and 0.596, respectively; all P<0.001). The incidence of T1DM and tuberculosis was significantly associated with the Organisation for Economic Cooperation and Development (OECD) status (P<0.001). After adjusting for GDP per capita, regional grouping, and OECD status, the incidence of T1DM negatively correlated with that of tuberculosis (R2 =0.729, P=0.009). However, there was no association between the BCG vaccination rate and incidence of T1DM (P=0.890). Conclusions There was a negative correlation between the incidence of tuberculosis and T1DM in children and adolescents aged <15 years at the country level.http://e-apem.org/upload/pdf/apem-2244254-127.pdfassociationtype 1 diabetes mellitus tuberculosis |
| spellingShingle | Ji Young Park Young June Choe Yaeji Lim Hyunsung Kim Jaehyun Kim Association between the incidence of type 1 diabetes mellitus and tuberculosis or bacillus Calmette-Guérin immunization in children and adolescents Annals of Pediatric Endocrinology & Metabolism association type 1 diabetes mellitus tuberculosis |
| title | Association between the incidence of type 1 diabetes mellitus and tuberculosis or bacillus Calmette-Guérin immunization in children and adolescents |
| title_full | Association between the incidence of type 1 diabetes mellitus and tuberculosis or bacillus Calmette-Guérin immunization in children and adolescents |
| title_fullStr | Association between the incidence of type 1 diabetes mellitus and tuberculosis or bacillus Calmette-Guérin immunization in children and adolescents |
| title_full_unstemmed | Association between the incidence of type 1 diabetes mellitus and tuberculosis or bacillus Calmette-Guérin immunization in children and adolescents |
| title_short | Association between the incidence of type 1 diabetes mellitus and tuberculosis or bacillus Calmette-Guérin immunization in children and adolescents |
| title_sort | association between the incidence of type 1 diabetes mellitus and tuberculosis or bacillus calmette guerin immunization in children and adolescents |
| topic | association type 1 diabetes mellitus tuberculosis |
| url | http://e-apem.org/upload/pdf/apem-2244254-127.pdf |
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