Multifaceted Genes in Amyotrophic Lateral Sclerosis-Frontotemporal Dementia

Multifaceted Genes in Amyotrophic Lateral Sclerosis-Frontotemporal Dementia

Amyotrophic lateral sclerosis and frontotemporal dementia are two progressive, adult onset neurodegenerative diseases, caused by the cell death of motor neurons in the motor cortex and spinal cord and cortical neurons in the frontal and temporal lobes, respectively. Whilst these have previously appe...

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Bibliographic Details
Main Authors: Ramya Ranganathan, Shaila Haque, Kayesha Coley, Stephanie Shepheard, Johnathan Cooper-Knock, Janine Kirby
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Neuroscience
Subjects:
ALS
FTD
C9orf72
RNA processing
autophagy
protein aggregation
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00684/full

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