Anterior-Segment Optical Coherence Tomography–Guided Measurement Of A Melting Ulcer For Follow-Up Of Corneoscleral Thinning Progression
Shai Cohen,1,2 Yisroel Tucker,3 Sharon Guttman,2,4 Ettel Bubis,2,3 Yair Rubinstein,3 Alon Skaat,2,5 Ifat Sher,2,3 Ygal Rotenstreich2,3 1Department of Ophthalmology, Assaf Harofeh Medical Center, Zerifin, Israel; 2Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel; 3Goldschleger Eye In...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2019-11-01
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| Series: | International Medical Case Reports Journal |
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| Online Access: | https://www.dovepress.com/anterior-segment-optical-coherence-tomography-guided-measurement-of-a--peer-reviewed-article-IMCRJ |
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| author | Cohen S Tucker Y Guttman S Bubis E Rubinstein Y Skaat A Sher I Rotenstreich Y |
| author_facet | Cohen S Tucker Y Guttman S Bubis E Rubinstein Y Skaat A Sher I Rotenstreich Y |
| author_sort | Cohen S |
| collection | DOAJ |
| description | Shai Cohen,1,2 Yisroel Tucker,3 Sharon Guttman,2,4 Ettel Bubis,2,3 Yair Rubinstein,3 Alon Skaat,2,5 Ifat Sher,2,3 Ygal Rotenstreich2,3 1Department of Ophthalmology, Assaf Harofeh Medical Center, Zerifin, Israel; 2Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel; 3Goldschleger Eye Institute, Sheba Medical Center, Tel Hashomer, Israel; 4Department of Ophthalmology, Assaf Harofeh Medical Center, Zerifin, Israel; 5Sam Rothberg Glaucoma Center, Goldschleger Eye Institute, Sheba Medical Center, Tel Hashomer, IsraelCorrespondence: Ygal RotenstreichGoldschleger Eye Institute, Sheba Medical Center, Derech Sheba 2, Tel-Hashomer, Ramat Gan, IsraelTel +972-3-5308132Email Ygal.Rotenstreich@sheba.health.gov.ilPurpose: To evaluate the feasibility of using anterior-segment optical coherence tomography (AS-OCT) for three-dimensional assessment of corneoscleral thinning progression in ulcers after pterygium removal.Methods: A patient with corneoscleral melting after pterygium removal surgery and mitomycin C treatment was evaluated using AS-OCT imaging of the corneoscleral ulcer at five consecutive time points, up to 2 years. AS-OCT scans of 8.3×5.6 mm (15°×10°) containing 41 B-scans spaced 139 μm apart were performed monthly for 4 months and then at 2 years following pterygium removal. A single B-scan was comprised of 768 A-scans. Ten B-scans of the same position were averaged in a single AS-OCT image. The area of ulcer’s section (AUS) was measured in seven fixed landmarks through a horizontally aligned plane in order to provide an estimation of the three-dimensional size of the lesion.Results: The AUS in the two superior locations increased during the follow-up period to an average of 114% at 2 years compared to the initial visit. In the other five locations (three midline and two inferior), the AUS decreased and was on average 64% in the midline and 29% in the inferior locations at 24 months.Conclusion: AS-OCT provided a readily available assessment of the lesion’s three-dimensional size during repeated follow-ups and identification of localized areas at higher risk for perforation. This method may potentially be useful for corneal surface pathologies requiring repeated follow-ups and may aid in decision-making regarding corneal thickness based on an accurate measurement.Keywords: anterior segment optical coherence tomography, corneoscleral melt, pterygium, corneoscleral thinning, ulcer follow up |
| first_indexed | 2024-12-18T11:34:55Z |
| format | Article |
| id | doaj.art-fbfe7696febf46ea8971b77622febc2b |
| institution | Directory Open Access Journal |
| issn | 1179-142X |
| language | English |
| last_indexed | 2024-12-18T11:34:55Z |
| publishDate | 2019-11-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Medical Case Reports Journal |
| spelling | doaj.art-fbfe7696febf46ea8971b77622febc2b2022-12-21T21:09:33ZengDove Medical PressInternational Medical Case Reports Journal1179-142X2019-11-01Volume 1233533849583Anterior-Segment Optical Coherence Tomography–Guided Measurement Of A Melting Ulcer For Follow-Up Of Corneoscleral Thinning ProgressionCohen STucker YGuttman SBubis ERubinstein YSkaat ASher IRotenstreich YShai Cohen,1,2 Yisroel Tucker,3 Sharon Guttman,2,4 Ettel Bubis,2,3 Yair Rubinstein,3 Alon Skaat,2,5 Ifat Sher,2,3 Ygal Rotenstreich2,3 1Department of Ophthalmology, Assaf Harofeh Medical Center, Zerifin, Israel; 2Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel; 3Goldschleger Eye Institute, Sheba Medical Center, Tel Hashomer, Israel; 4Department of Ophthalmology, Assaf Harofeh Medical Center, Zerifin, Israel; 5Sam Rothberg Glaucoma Center, Goldschleger Eye Institute, Sheba Medical Center, Tel Hashomer, IsraelCorrespondence: Ygal RotenstreichGoldschleger Eye Institute, Sheba Medical Center, Derech Sheba 2, Tel-Hashomer, Ramat Gan, IsraelTel +972-3-5308132Email Ygal.Rotenstreich@sheba.health.gov.ilPurpose: To evaluate the feasibility of using anterior-segment optical coherence tomography (AS-OCT) for three-dimensional assessment of corneoscleral thinning progression in ulcers after pterygium removal.Methods: A patient with corneoscleral melting after pterygium removal surgery and mitomycin C treatment was evaluated using AS-OCT imaging of the corneoscleral ulcer at five consecutive time points, up to 2 years. AS-OCT scans of 8.3×5.6 mm (15°×10°) containing 41 B-scans spaced 139 μm apart were performed monthly for 4 months and then at 2 years following pterygium removal. A single B-scan was comprised of 768 A-scans. Ten B-scans of the same position were averaged in a single AS-OCT image. The area of ulcer’s section (AUS) was measured in seven fixed landmarks through a horizontally aligned plane in order to provide an estimation of the three-dimensional size of the lesion.Results: The AUS in the two superior locations increased during the follow-up period to an average of 114% at 2 years compared to the initial visit. In the other five locations (three midline and two inferior), the AUS decreased and was on average 64% in the midline and 29% in the inferior locations at 24 months.Conclusion: AS-OCT provided a readily available assessment of the lesion’s three-dimensional size during repeated follow-ups and identification of localized areas at higher risk for perforation. This method may potentially be useful for corneal surface pathologies requiring repeated follow-ups and may aid in decision-making regarding corneal thickness based on an accurate measurement.Keywords: anterior segment optical coherence tomography, corneoscleral melt, pterygium, corneoscleral thinning, ulcer follow uphttps://www.dovepress.com/anterior-segment-optical-coherence-tomography-guided-measurement-of-a--peer-reviewed-article-IMCRJanterior segment optical coherence tomographycorneoscleral meltpterygiumcorneoscleral thinningulcer follow up |
| spellingShingle | Cohen S Tucker Y Guttman S Bubis E Rubinstein Y Skaat A Sher I Rotenstreich Y Anterior-Segment Optical Coherence Tomography–Guided Measurement Of A Melting Ulcer For Follow-Up Of Corneoscleral Thinning Progression International Medical Case Reports Journal anterior segment optical coherence tomography corneoscleral melt pterygium corneoscleral thinning ulcer follow up |
| title | Anterior-Segment Optical Coherence Tomography–Guided Measurement Of A Melting Ulcer For Follow-Up Of Corneoscleral Thinning Progression |
| title_full | Anterior-Segment Optical Coherence Tomography–Guided Measurement Of A Melting Ulcer For Follow-Up Of Corneoscleral Thinning Progression |
| title_fullStr | Anterior-Segment Optical Coherence Tomography–Guided Measurement Of A Melting Ulcer For Follow-Up Of Corneoscleral Thinning Progression |
| title_full_unstemmed | Anterior-Segment Optical Coherence Tomography–Guided Measurement Of A Melting Ulcer For Follow-Up Of Corneoscleral Thinning Progression |
| title_short | Anterior-Segment Optical Coherence Tomography–Guided Measurement Of A Melting Ulcer For Follow-Up Of Corneoscleral Thinning Progression |
| title_sort | anterior segment optical coherence tomography guided measurement of a melting ulcer for follow up of corneoscleral thinning progression |
| topic | anterior segment optical coherence tomography corneoscleral melt pterygium corneoscleral thinning ulcer follow up |
| url | https://www.dovepress.com/anterior-segment-optical-coherence-tomography-guided-measurement-of-a--peer-reviewed-article-IMCRJ |
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