Prevalence of bacteria isolated from patients with burn infection at a burn hospital in Baghdad and study of their antimicrobial susceptibility patterns
Background: The skin functions as a barrier to the external environment, damage to this barrier following a burn disrupts the innate immune system and increases susceptibility to bacterial infection. Objective: This study was carried out to determine the bacterial isolates and study their antimicro...
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| Format: | Article |
| Language: | English |
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University of Baghdad/ Al-Kindy College of Medicine
2016-06-01
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| Series: | مجله كليه طب الكندي |
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| Online Access: | https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/345 |
| _version_ | 1811275430819266560 |
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| author | Saad L. Hamed Khetam H. Rasool Nadheema H. Hussein Butheina Mahamed Taha |
| author_facet | Saad L. Hamed Khetam H. Rasool Nadheema H. Hussein Butheina Mahamed Taha |
| author_sort | Saad L. Hamed |
| collection | DOAJ |
| description |
Background: The skin functions as a barrier to the external environment, damage to this barrier following a burn disrupts the innate immune system and increases susceptibility to bacterial infection. Objective: This study was carried out to determine the bacterial isolates and study their antimicrobial susceptibility in burned wound infections at one burn's hospital in Baghdad.Type of study:Cross-sectional study.Methods: The bacteria were identified at species level by using Analytic Profile Index (API) system and The antimicrobial susceptibility test was performed according to Kirby-Bauer (disk diffusion) technique.Results: Over a period of one year (from October 2014 to October 2015). Out of 848 patients with different degrees of burns, 186 (19.81%) positive bacterial isolates. Out of 186 bacterial isolates, the isolation rate of Gram positive was 14(7.53%) and Gram negative isolates was 172(92.47%). From those 172 Gram negative bacteria the most frequently isolated bacteria was Pseudomonas aeruginosa 60(32.26%) isolates followed by Acinetobacter baumannii 40(21.51) and all Gram positive bacteria were Staphylococcus aureus 14(7.53). The most effective antibiotic on Staphylococcus aureus isolates was Vancomycin (sensitivity rate was 11(92.86%)), while the highest resistance was to Penicillin and the rate of resistance was 14(100%) followed by Ampicillin 12(85.71%). The most effective antibiotic on Gram-Negative isolates was Imipenem (sensitivity rate was 165(95.93%)) followed by Amikacin (sensitivity rate was 146(84.88%)). On the other hand the Gram negative bacteria in this study were mostly resistant to Ampicillin 164(95.35%) and Amoxicillin-Clavulanic acid 157(91.28). Acinetobacter baumannii and Klebsiella pneumoniae isolates were the mostly resistant isolates than other gram negative bacteria under this study.Conclusion: Pseudomonas aeruginosa was the most frequently isolated bacteria among gram negative bacteria and the most effective antibiotics on Gram-Negative and Staphylococcus aureus isolates were Imipenem and Vancomycin, respectively.
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| first_indexed | 2024-04-12T23:38:48Z |
| format | Article |
| id | doaj.art-fc00433531c44e31b2ca1eebe21495f3 |
| institution | Directory Open Access Journal |
| issn | 1810-9543 2521-4365 |
| language | English |
| last_indexed | 2024-04-12T23:38:48Z |
| publishDate | 2016-06-01 |
| publisher | University of Baghdad/ Al-Kindy College of Medicine |
| record_format | Article |
| series | مجله كليه طب الكندي |
| spelling | doaj.art-fc00433531c44e31b2ca1eebe21495f32022-12-22T03:12:04ZengUniversity of Baghdad/ Al-Kindy College of Medicineمجله كليه طب الكندي1810-95432521-43652016-06-01121Prevalence of bacteria isolated from patients with burn infection at a burn hospital in Baghdad and study of their antimicrobial susceptibility patternsSaad L. Hamed0Khetam H. RasoolNadheema H. HusseinButheina Mahamed Taha-Department of Biology, College of Science, Al-Mustansiryah University Background: The skin functions as a barrier to the external environment, damage to this barrier following a burn disrupts the innate immune system and increases susceptibility to bacterial infection. Objective: This study was carried out to determine the bacterial isolates and study their antimicrobial susceptibility in burned wound infections at one burn's hospital in Baghdad.Type of study:Cross-sectional study.Methods: The bacteria were identified at species level by using Analytic Profile Index (API) system and The antimicrobial susceptibility test was performed according to Kirby-Bauer (disk diffusion) technique.Results: Over a period of one year (from October 2014 to October 2015). Out of 848 patients with different degrees of burns, 186 (19.81%) positive bacterial isolates. Out of 186 bacterial isolates, the isolation rate of Gram positive was 14(7.53%) and Gram negative isolates was 172(92.47%). From those 172 Gram negative bacteria the most frequently isolated bacteria was Pseudomonas aeruginosa 60(32.26%) isolates followed by Acinetobacter baumannii 40(21.51) and all Gram positive bacteria were Staphylococcus aureus 14(7.53). The most effective antibiotic on Staphylococcus aureus isolates was Vancomycin (sensitivity rate was 11(92.86%)), while the highest resistance was to Penicillin and the rate of resistance was 14(100%) followed by Ampicillin 12(85.71%). The most effective antibiotic on Gram-Negative isolates was Imipenem (sensitivity rate was 165(95.93%)) followed by Amikacin (sensitivity rate was 146(84.88%)). On the other hand the Gram negative bacteria in this study were mostly resistant to Ampicillin 164(95.35%) and Amoxicillin-Clavulanic acid 157(91.28). Acinetobacter baumannii and Klebsiella pneumoniae isolates were the mostly resistant isolates than other gram negative bacteria under this study.Conclusion: Pseudomonas aeruginosa was the most frequently isolated bacteria among gram negative bacteria and the most effective antibiotics on Gram-Negative and Staphylococcus aureus isolates were Imipenem and Vancomycin, respectively. https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/345BurnsGram-Negative bacteriaStaphylococcus aureus and Antimicrobial susceptibility test |
| spellingShingle | Saad L. Hamed Khetam H. Rasool Nadheema H. Hussein Butheina Mahamed Taha Prevalence of bacteria isolated from patients with burn infection at a burn hospital in Baghdad and study of their antimicrobial susceptibility patterns مجله كليه طب الكندي Burns Gram-Negative bacteria Staphylococcus aureus and Antimicrobial susceptibility test |
| title | Prevalence of bacteria isolated from patients with burn infection at a burn hospital in Baghdad and study of their antimicrobial susceptibility patterns |
| title_full | Prevalence of bacteria isolated from patients with burn infection at a burn hospital in Baghdad and study of their antimicrobial susceptibility patterns |
| title_fullStr | Prevalence of bacteria isolated from patients with burn infection at a burn hospital in Baghdad and study of their antimicrobial susceptibility patterns |
| title_full_unstemmed | Prevalence of bacteria isolated from patients with burn infection at a burn hospital in Baghdad and study of their antimicrobial susceptibility patterns |
| title_short | Prevalence of bacteria isolated from patients with burn infection at a burn hospital in Baghdad and study of their antimicrobial susceptibility patterns |
| title_sort | prevalence of bacteria isolated from patients with burn infection at a burn hospital in baghdad and study of their antimicrobial susceptibility patterns |
| topic | Burns Gram-Negative bacteria Staphylococcus aureus and Antimicrobial susceptibility test |
| url | https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/345 |
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