Status of Pathology Services and Molecular Pathology in Sub-Saharan Africa: Implications for Combating Breast Cancer
African breast cancer patients benefit less from classical pathology services owing to the complex molecular and clinicopathological nature of the disease, poor quality of laboratory supplies, and shortage of experts in the field. This review presents evidence and confirms the need for improving ana...
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| Format: | Article |
| Language: | English |
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The Korean Society for Clinical Laboratory Science
2023-09-01
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| Series: | Korean Journal of Clinical Laboratory Science |
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| Online Access: | http://www.kjcls.org/journal/view.html?doi=10.15324/kjcls.2023.55.3.121 |
| _version_ | 1797666617683869696 |
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| author | Wajana Lako LABISSO |
| author_facet | Wajana Lako LABISSO |
| author_sort | Wajana Lako LABISSO |
| collection | DOAJ |
| description | African breast cancer patients benefit less from classical pathology services owing to the complex molecular and clinicopathological nature of the disease, poor quality of laboratory supplies, and shortage of experts in the field. This review presents evidence and confirms the need for improving anatomic pathology services in Africa. Peer-reviewed international journal articles available in Medline, Scopus, PubMed, and Google scholars, describing the status of pathology services in Africa, were included. Besides the late presentation of patients, anatomic pathology laboratories are accountable for the escalated mortality of breast cancer patients in several parts of Africa. Conversely, molecular diversity and biological heterogeneity of breast cancers, which disprove the one-size-fits-all therapeutic approach, have been reported from different parts of the continent. Irrespective of the geographical background, the choice of therapeutic options and predicting disease outcome depends on the right identification of the molecular signature of the cancer type. In conclusion, we propose that upgrading and integrating anatomic pathology with molecular diagnostic pathology is essential in order to provide better diagnostic results that will profoundly impact curbing mortality from breast cancers. |
| first_indexed | 2024-03-11T20:01:00Z |
| format | Article |
| id | doaj.art-fc017b08f8664dc9822b656e94131b91 |
| institution | Directory Open Access Journal |
| issn | 1738-3544 |
| language | English |
| last_indexed | 2024-03-11T20:01:00Z |
| publishDate | 2023-09-01 |
| publisher | The Korean Society for Clinical Laboratory Science |
| record_format | Article |
| series | Korean Journal of Clinical Laboratory Science |
| spelling | doaj.art-fc017b08f8664dc9822b656e94131b912023-10-04T08:29:13ZengThe Korean Society for Clinical Laboratory ScienceKorean Journal of Clinical Laboratory Science1738-35442023-09-0155312113110.15324/kjcls.2023.55.3.121kjcls.2023.55.3.121Status of Pathology Services and Molecular Pathology in Sub-Saharan Africa: Implications for Combating Breast CancerWajana Lako LABISSO0Department of Pathology, School of Medicine, Addis Ababa University, Addis Ababa, EthiopiaAfrican breast cancer patients benefit less from classical pathology services owing to the complex molecular and clinicopathological nature of the disease, poor quality of laboratory supplies, and shortage of experts in the field. This review presents evidence and confirms the need for improving anatomic pathology services in Africa. Peer-reviewed international journal articles available in Medline, Scopus, PubMed, and Google scholars, describing the status of pathology services in Africa, were included. Besides the late presentation of patients, anatomic pathology laboratories are accountable for the escalated mortality of breast cancer patients in several parts of Africa. Conversely, molecular diversity and biological heterogeneity of breast cancers, which disprove the one-size-fits-all therapeutic approach, have been reported from different parts of the continent. Irrespective of the geographical background, the choice of therapeutic options and predicting disease outcome depends on the right identification of the molecular signature of the cancer type. In conclusion, we propose that upgrading and integrating anatomic pathology with molecular diagnostic pathology is essential in order to provide better diagnostic results that will profoundly impact curbing mortality from breast cancers.http://www.kjcls.org/journal/view.html?doi=10.15324/kjcls.2023.55.3.121africa south of the saharabreast neoplasmspathologymolecularpathology services |
| spellingShingle | Wajana Lako LABISSO Status of Pathology Services and Molecular Pathology in Sub-Saharan Africa: Implications for Combating Breast Cancer Korean Journal of Clinical Laboratory Science africa south of the sahara breast neoplasms pathology molecular pathology services |
| title | Status of Pathology Services and Molecular Pathology in Sub-Saharan Africa: Implications for Combating Breast Cancer |
| title_full | Status of Pathology Services and Molecular Pathology in Sub-Saharan Africa: Implications for Combating Breast Cancer |
| title_fullStr | Status of Pathology Services and Molecular Pathology in Sub-Saharan Africa: Implications for Combating Breast Cancer |
| title_full_unstemmed | Status of Pathology Services and Molecular Pathology in Sub-Saharan Africa: Implications for Combating Breast Cancer |
| title_short | Status of Pathology Services and Molecular Pathology in Sub-Saharan Africa: Implications for Combating Breast Cancer |
| title_sort | status of pathology services and molecular pathology in sub saharan africa implications for combating breast cancer |
| topic | africa south of the sahara breast neoplasms pathology molecular pathology services |
| url | http://www.kjcls.org/journal/view.html?doi=10.15324/kjcls.2023.55.3.121 |
| work_keys_str_mv | AT wajanalakolabisso statusofpathologyservicesandmolecularpathologyinsubsaharanafricaimplicationsforcombatingbreastcancer |