Targeted metabolomics of sulfated bile acids in urine for the diagnosis and grading of intrahepatic cholestasis of pregnancy

Targeted metabolomics of sulfated bile acids in urine for the diagnosis and grading of intrahepatic cholestasis of pregnancy

Intrahepatic cholestasis of pregnancy (ICP) is related to cholestatic disorder in pregnancy. Total urinary sulfated bile acids (SBAs) were found increased in ICP. We distinguished the metabolic profiling of urinary SBAs in ICP to find potential biomarkers for the diagnosis and grading of ICP. The ta...

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Bibliographic Details
Main Authors: Yuchao Li, Xiaoqing Zhang, Jianbo Chen, Chengya Feng, Yifan He, Yong Shao, Min Ding
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2018-12-01
Series:Genes and Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304218300102

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