Human Trypanosoma cruzi Infection and Seropositivity in Dogs, Mexico

We used 5 diagnostic tests in a cross-sectional investigation of the prevalence of Trypanosoma cruzi in Tejupilco municipality, State of Mexico, Mexico. Our findings showed a substantial prevalence of immunoglobulin G (IgG) and IgM antibodies to T. cruzi in human (n = 293, IgG 2.05%, IgM 5.5%, both...

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Bibliographic Details
Main Authors: Jose G. Estrada-Franco, Vandanajay Bhatia, Hector Diaz-Albiter, Laucel Ochoa-Garcia, Alberto Barbabosa, Juan C. Vazquez-Chagoyan, Miguel A. Martinez-Perez, Carmen Guzman-Bracho, Nisha Garg
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2006-04-01
Series:Emerging Infectious Diseases
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Online Access:https://wwwnc.cdc.gov/eid/article/12/4/05-0450_article
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Summary:We used 5 diagnostic tests in a cross-sectional investigation of the prevalence of Trypanosoma cruzi in Tejupilco municipality, State of Mexico, Mexico. Our findings showed a substantial prevalence of immunoglobulin G (IgG) and IgM antibodies to T. cruzi in human (n = 293, IgG 2.05%, IgM 5.5%, both 7.1%) and dog (n = 114, IgG 15.8%, IgM 11.4%, both 21%) populations. We also found antibodies to T. cruzi (n = 80, IgG 10%, IgM 15%, both 17.5%) in dogs from Toluca, an area previously considered free of T. cruzi. Our data demonstrate the need for active epidemiologic surveillance programs in these regions. A direct correlation (r2 = 0.955) of seropositivity between humans and dogs suggests that seroanalysis in dogs may help identify the human prevalence of T. cruzi infection in these areas.
ISSN:1080-6040
1080-6059