Route of Arsenic Exposure Differentially Impacts the Expression of Genes Involved in Gut-Mucosa-Associated Immune Responses and Gastrointestinal Permeability
First-pass metabolism alters arsenic biotransformation and its immunomodulatory activities. This study aims to determine the mRNA expression of intestinal-immunity- and permeability-associated genes, levels of cytokine/chemokines and levels of immunoglobulin isotypes when CD-1 mice were exposed to a...
Main Authors: | Kuppan Gokulan, Aakriti Mathur, Amit Kumar, Michelle M. Vanlandingham, Sangeeta Khare |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-03-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/24/7/6352 |
Similar Items
-
Preclinical In Vitro Model to Assess the Changes in Permeability and Cytotoxicity of Polarized Intestinal Epithelial Cells during Exposure Mimicking Oral or Intravenous Routes: An Example of Arsenite Exposure
by: Pravin Parajuli, et al.
Published: (2022-04-01) -
Human Intestinal Tissue Explant Exposure to Silver Nanoparticles Reveals Sex Dependent Alterations in Inflammatory Responses and Epithelial Cell Permeability
by: Kuppan Gokulan, et al.
Published: (2020-12-01) -
Arsenic in Drinking Water and Diabetes
by: Aryatara Shakya, et al.
Published: (2023-05-01) -
Determinants of arsenic methylation efficiency and urinary arsenic level in pregnant women in Bangladesh
by: Shangzhi Gao, et al.
Published: (2019-11-01) -
Environmental Source of Arsenic Exposure
by: Jin-Yong Chung, et al.
Published: (2014-09-01)