Prevalence of metabolic syndrome among obese diabetic subjects
Background: Metabolic syndrome (MS) is a cluster of metabolic risk factors including obesity, glucose intolerance, insulin resistance, dyslipidemia and hypertension. MS in obese and type 2 diabetic (T2DM) subjects increases the risk of cardiovascular diseases (CVD). The objective of the present stud...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Advance Educational Institute & Research Centre
2015-12-01
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| Series: | International Journal of Endorsing Health Science Research |
| Subjects: | |
| Online Access: | http://aeirc-edu.com/ojs14/index.php/IJEHSR/article/view/112/367 |
| _version_ | 1818823987379044352 |
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| author | Mehwish Zeeshan Muhammad Imran Humaira Jabeen Sumreen Begum Nazia Ahmed Rashida Qasim |
| author_facet | Mehwish Zeeshan Muhammad Imran Humaira Jabeen Sumreen Begum Nazia Ahmed Rashida Qasim |
| author_sort | Mehwish Zeeshan |
| collection | DOAJ |
| description | Background: Metabolic syndrome (MS) is a cluster of metabolic risk factors including obesity, glucose intolerance, insulin resistance, dyslipidemia and hypertension. MS in obese and type 2 diabetic (T2DM) subjects increases the risk of cardiovascular diseases (CVD). The objective of the present study is to estimate the prevalence of MS in obese T2DM subjects by using International Diabetes Federation (IDF) and National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATP III) definitions.
Methods: Obese T2DM (n=70) and normal healthy subjects (n=30) of both genders were selected from hospitals and diabetic centers of various localities of Karachi, Pakistan. The frequency of MS was estimated by utilizing criteria of the proposed definitions of IDF and NCEP-ATP III.
Results: The prevalence of MS using IDF definition in obeseT2DM subjects was 85.7%. It is significantly higher (p≤0.05) in females (45.70%) as compared to males (30.0%). While, using NCEP-ATP III definition the overall prevalence of MS in obese T2DM subjects was 75.7%, the prevalence is significantly higher (p≤0.05) in females (47.1%) than males (38.6%). The development of MS was highly observed between 31 – 40 years of age under criteria of both definitions.
Conclusion It is concluded that, the overall prevalence of MS is increasing significantly in obese T2DM subjects by using IDF and NCEP – ATP III definitions. However, IDF is more stringent for defining MS. Therefore, it is needed to initiate the preventive measures of a healthy lifestyle and emphasis should be given to reduce weight, increase physical activity, and increase intake of healthy low-glycemic-index foods. |
| first_indexed | 2024-12-18T23:48:42Z |
| format | Article |
| id | doaj.art-fc09b393bb7b4970928c1e4f7fae6b32 |
| institution | Directory Open Access Journal |
| issn | 2307-3748 2310-3841 |
| language | English |
| last_indexed | 2024-12-18T23:48:42Z |
| publishDate | 2015-12-01 |
| publisher | Advance Educational Institute & Research Centre |
| record_format | Article |
| series | International Journal of Endorsing Health Science Research |
| spelling | doaj.art-fc09b393bb7b4970928c1e4f7fae6b322022-12-21T20:47:08ZengAdvance Educational Institute & Research CentreInternational Journal of Endorsing Health Science Research2307-37482310-38412015-12-01342328https://doi.org/10.29052/IJEHSR.v3.i4.2015.23-28Prevalence of metabolic syndrome among obese diabetic subjectsMehwish Zeeshan0Muhammad Imran1Humaira Jabeen2Sumreen Begum3Nazia Ahmed4Rashida Qasim5College of Allied Health Sciences, Ziauddin University, KarachiCollege of Allied Health Sciences, Ziauddin University, KarachiCollege of Allied Health Sciences, Ziauddin University, KarachiCollege of Allied Health Sciences, Ziauddin University, KarachiCollege of Allied Health Sciences, Ziauddin University, KarachiCollege of Allied Health Sciences, Ziauddin University, KarachiBackground: Metabolic syndrome (MS) is a cluster of metabolic risk factors including obesity, glucose intolerance, insulin resistance, dyslipidemia and hypertension. MS in obese and type 2 diabetic (T2DM) subjects increases the risk of cardiovascular diseases (CVD). The objective of the present study is to estimate the prevalence of MS in obese T2DM subjects by using International Diabetes Federation (IDF) and National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATP III) definitions. Methods: Obese T2DM (n=70) and normal healthy subjects (n=30) of both genders were selected from hospitals and diabetic centers of various localities of Karachi, Pakistan. The frequency of MS was estimated by utilizing criteria of the proposed definitions of IDF and NCEP-ATP III. Results: The prevalence of MS using IDF definition in obeseT2DM subjects was 85.7%. It is significantly higher (p≤0.05) in females (45.70%) as compared to males (30.0%). While, using NCEP-ATP III definition the overall prevalence of MS in obese T2DM subjects was 75.7%, the prevalence is significantly higher (p≤0.05) in females (47.1%) than males (38.6%). The development of MS was highly observed between 31 – 40 years of age under criteria of both definitions. Conclusion It is concluded that, the overall prevalence of MS is increasing significantly in obese T2DM subjects by using IDF and NCEP – ATP III definitions. However, IDF is more stringent for defining MS. Therefore, it is needed to initiate the preventive measures of a healthy lifestyle and emphasis should be given to reduce weight, increase physical activity, and increase intake of healthy low-glycemic-index foods.http://aeirc-edu.com/ojs14/index.php/IJEHSR/article/view/112/367metabolic syndromediabetes mellitusinsulin resistance obesityatherosclerotic cardiovascular diseaseidfncep-atp iii |
| spellingShingle | Mehwish Zeeshan Muhammad Imran Humaira Jabeen Sumreen Begum Nazia Ahmed Rashida Qasim Prevalence of metabolic syndrome among obese diabetic subjects International Journal of Endorsing Health Science Research metabolic syndrome diabetes mellitus insulin resistance obesity atherosclerotic cardiovascular disease idf ncep-atp iii |
| title | Prevalence of metabolic syndrome among obese diabetic subjects |
| title_full | Prevalence of metabolic syndrome among obese diabetic subjects |
| title_fullStr | Prevalence of metabolic syndrome among obese diabetic subjects |
| title_full_unstemmed | Prevalence of metabolic syndrome among obese diabetic subjects |
| title_short | Prevalence of metabolic syndrome among obese diabetic subjects |
| title_sort | prevalence of metabolic syndrome among obese diabetic subjects |
| topic | metabolic syndrome diabetes mellitus insulin resistance obesity atherosclerotic cardiovascular disease idf ncep-atp iii |
| url | http://aeirc-edu.com/ojs14/index.php/IJEHSR/article/view/112/367 |
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