Seroprevalence of brucellosis among the high-risk population in Ujjain district, Madhya Pradesh
Background: Brucellosis is the most common zoonotic disease caused by Gram-negative coccobacillus belonging to genus Brucella. It is a recognized public health problem in developing countries including India. Aims and Objectives: The aims of these study were to determine the seroprevalance of bru...
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| Format: | Article |
| Language: | English |
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Manipal College of Medical Sciences, Pokhara
2022-10-01
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| Series: | Asian Journal of Medical Sciences |
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| Online Access: | https://www.nepjol.info/index.php/AJMS/article/view/45698 |
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| author | Riddhi Pradhan Anand Bhadkariya Vidit Khandelawal Vishal Diwan Waghe SR Deepak Saxena Shah H Manju Purohit |
| author_facet | Riddhi Pradhan Anand Bhadkariya Vidit Khandelawal Vishal Diwan Waghe SR Deepak Saxena Shah H Manju Purohit |
| author_sort | Riddhi Pradhan |
| collection | DOAJ |
| description | Background: Brucellosis is the most common zoonotic disease caused by Gram-negative coccobacillus belonging to genus Brucella. It is a recognized public health problem in developing countries including India.
Aims and Objectives: The aims of these study were to determine the seroprevalance of brucellosis in population having occupation dealing with animals and thus are in close contact of animals.
Materials and Methods: The study was conducted in semi-urban areas of central India. Blood samples were collected from personnel working in slaughter houses, meat shops, and veterinarians and their close contact and who are willing to participate in study. A total 102 samples collected randomly from butchers (n=20), veterinarians (n=29), and animal handlers (n=53) and were tested for Brucella abortus and Brucella melitensis by a commercial kit which allows the detection of both complete (IgG and IGM) and incomplete antibodies.
Results: A total 102 subjects were included in the study and overall prevalence of brucellosis among high-risk group was found to be 2.9%. One veterinarian doctor was also found positive for both B. melitensis and B. abortus. Highest prevalence of brucellosis was found in veterinarians (6.8%) followed by animal handlers (1.8%), and none of the butcher was tested positive for any of the Brucella antibody.
Conclusion: The present study screened all possible known high-risk groups for brucellosis and revealed that veterinarians have high chances of getting the infection. Occupation-related disease like brucellosis needs regular surveillance and integration into control and prevention program at a local and national level. |
| first_indexed | 2024-04-12T09:49:23Z |
| format | Article |
| id | doaj.art-fc09b5ee1dfb46a4a336ee9d3ca9dbf5 |
| institution | Directory Open Access Journal |
| issn | 2467-9100 2091-0576 |
| language | English |
| last_indexed | 2024-04-12T09:49:23Z |
| publishDate | 2022-10-01 |
| publisher | Manipal College of Medical Sciences, Pokhara |
| record_format | Article |
| series | Asian Journal of Medical Sciences |
| spelling | doaj.art-fc09b5ee1dfb46a4a336ee9d3ca9dbf52022-12-22T03:37:52ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762022-10-011310183187https://doi.org/10.3126/ajms.v13i10.45698Seroprevalence of brucellosis among the high-risk population in Ujjain district, Madhya PradeshRiddhi Pradhan 0https://orcid.org/0000-0003-1848-2370Anand Bhadkariya 1https://orcid.org/0000-0001-6413-9421Vidit Khandelawal 2https://orcid.org/0000-0003-4161-6381Vishal Diwan 3https://orcid.org/0000-0001-7948-8579Waghe SR 4https://orcid.org/0000-0002-4473-8977Deepak Saxena 5https://orcid.org/0000-0003-0563-4259Shah H6https://orcid.org/0000-0002-5982-1909Manju Purohit 7https://orcid.org/0000-0001-5385-7305Associate professor Department of Microbiology, R. D. Gardi Medical College, Ujjain, India Professor, Department of Pathology Government Medical College, Datia, Madhya Pradesh, India Associate Professor, Department of Community Medicine, R. D. Gardi Medical College, Ujjain, Madhya Pradesh, India Scientist-E and Head Environmental Monitoring & Exposure Assessment(Water & Soil) ICMR-National Institute of Research in Environment Health, Bhopal, Madhya Pradesh, India Veterinary Officer, Department of Pharmacology, R. D. Gardi Medical College, Ujjain, Madhya Pradesh, India Professor, Department of Community Medicine Indian Institute of Public Health, Gandhi Nagar, Gujarat, India Professor, Department of Microbiology, Vedantaa Medical College, Dhanu, Maharashtra, India Professor and Head, Department of Pathology, R. D. Gardi Medical College, Ujjain, Madhya Pradesh, India and Professor, Department of Public Health Science, Karolinska Institute, Sweden Background: Brucellosis is the most common zoonotic disease caused by Gram-negative coccobacillus belonging to genus Brucella. It is a recognized public health problem in developing countries including India. Aims and Objectives: The aims of these study were to determine the seroprevalance of brucellosis in population having occupation dealing with animals and thus are in close contact of animals. Materials and Methods: The study was conducted in semi-urban areas of central India. Blood samples were collected from personnel working in slaughter houses, meat shops, and veterinarians and their close contact and who are willing to participate in study. A total 102 samples collected randomly from butchers (n=20), veterinarians (n=29), and animal handlers (n=53) and were tested for Brucella abortus and Brucella melitensis by a commercial kit which allows the detection of both complete (IgG and IGM) and incomplete antibodies. Results: A total 102 subjects were included in the study and overall prevalence of brucellosis among high-risk group was found to be 2.9%. One veterinarian doctor was also found positive for both B. melitensis and B. abortus. Highest prevalence of brucellosis was found in veterinarians (6.8%) followed by animal handlers (1.8%), and none of the butcher was tested positive for any of the Brucella antibody. Conclusion: The present study screened all possible known high-risk groups for brucellosis and revealed that veterinarians have high chances of getting the infection. Occupation-related disease like brucellosis needs regular surveillance and integration into control and prevention program at a local and national level.https://www.nepjol.info/index.php/AJMS/article/view/45698brucellosis; high risk; prevalence; india |
| spellingShingle | Riddhi Pradhan Anand Bhadkariya Vidit Khandelawal Vishal Diwan Waghe SR Deepak Saxena Shah H Manju Purohit Seroprevalence of brucellosis among the high-risk population in Ujjain district, Madhya Pradesh Asian Journal of Medical Sciences brucellosis; high risk; prevalence; india |
| title | Seroprevalence of brucellosis among the high-risk population in Ujjain district, Madhya Pradesh |
| title_full | Seroprevalence of brucellosis among the high-risk population in Ujjain district, Madhya Pradesh |
| title_fullStr | Seroprevalence of brucellosis among the high-risk population in Ujjain district, Madhya Pradesh |
| title_full_unstemmed | Seroprevalence of brucellosis among the high-risk population in Ujjain district, Madhya Pradesh |
| title_short | Seroprevalence of brucellosis among the high-risk population in Ujjain district, Madhya Pradesh |
| title_sort | seroprevalence of brucellosis among the high risk population in ujjain district madhya pradesh |
| topic | brucellosis; high risk; prevalence; india |
| url | https://www.nepjol.info/index.php/AJMS/article/view/45698 |
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