Proteasomal Degradation Machinery: Favorite Target of HIV-1 Proteins

Proteasomal Degradation Machinery: Favorite Target of HIV-1 Proteins

Proteasomal degradation pathways play a central role in regulating a variety of protein functions by controlling not only their turnover but also the physiological behavior of the cell. This makes it an attractive target for the pathogens, especially viruses which rely on the host cellular machinery...

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Bibliographic Details
Main Authors: Sneh Lata, Ritu Mishra, Akhil C. Banerjea
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Microbiology
Subjects:
proteasome
proteasome 20S
ubiquitination
deubiquitinase (DUB)
HIV-1
Tat
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.02738/full

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