The Cleaning Effect of the Photocatalysis of TiO2-B＠anatase Nanowires on Biological Activity on a Titanium Surface
Yan Gao,1 Xi Lin,1 Yadong Zhao,2 Shulan Xu,1 Chunhua Lai,1 Zehong Guo,1 Wangxi Wu,1 Xianglong Ding,1 Fang Jia,1 Lei Zhou,1 Ying Liu3 1Center of Oral Implantology, Stomatological Hospital, Southern Medical University, Guangzhou 510280, People’s Republic of China; 2Department of Oral and Max...
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2020-12-01
|
| Series: | International Journal of Nanomedicine |
| Subjects: | |
| Online Access: | https://www.dovepress.com/the-cleaning-effect-of-the-photocatalysis-of-tio2-banatase-nanowires-o-peer-reviewed-article-IJN |
| _version_ | 1818842646884384768 |
|---|---|
| author | Gao Y Lin X Zhao Y Xu S Lai C Guo Z Wu W Ding X Jia F Zhou L Liu Y |
| author_facet | Gao Y Lin X Zhao Y Xu S Lai C Guo Z Wu W Ding X Jia F Zhou L Liu Y |
| author_sort | Gao Y |
| collection | DOAJ |
| description | Yan Gao,1 Xi Lin,1 Yadong Zhao,2 Shulan Xu,1 Chunhua Lai,1 Zehong Guo,1 Wangxi Wu,1 Xianglong Ding,1 Fang Jia,1 Lei Zhou,1 Ying Liu3 1Center of Oral Implantology, Stomatological Hospital, Southern Medical University, Guangzhou 510280, People’s Republic of China; 2Department of Oral and Maxillofacial Surgery, Inner Mongolia People’ Hospital, Huhhot, Inner Mongolia 010017, People’s Republic of China; 3Department of Endodontics, Stomatological Hospital, Southern Medical University, Guangzhou 510280, People’s Republic of ChinaCorrespondence: Ying LiuDepartment of Endodontics, Stomatological Hospital, Southern Medical University, 366 South Jiang Nan Road, Hai Zhu District, Guangzhou 510280, People’s Republic of ChinaTel +86-20-84408890Fax +86-20-84433177Email 286668937@smu.edu.cnBackground: Improvements in the early osseointegration of titanium implants require investigations on the bone-implant interface, which is a critical and complex challenge. The surface cleanliness of titanium implants plays an important role at this interface. However, the implant surface would inevitably absorb contamination such as organic hydrocarbons, which is not conductive to the establishment of early osseointegration. Herein, an optimized approach for removing contamination from titanium surfaces was studied.Methods: The TiO2-B＠anatase NWs (nanowires) were prepared on titanium substrates through a hydrothermal process. A methylene blue degradation experiment was performed to assess the photodegradation activity. The cleaning effect of the photocatalysis of TiO2-B＠anatase NWs on a titanium surface and the cellular early response was determined by analyzing cell morphology, attachment, proliferation and differentiation.Results: The results indicated that the photocatalysis of TiO2-B＠anatase NWs could effectively remove hydrocarbons on titanium surfaces without sacrificing the favourable titanium surface morphology. The methylene blue degradation experiment revealed that the photocatalysis of TiO2-B＠anatase NWs had powerful degradation activity, which is attributed to the presence of strong oxidants such as ·OH. In addition, compared to the merely ultraviolet-treated titanium surfaces, the titanium surfaces treated after the NWs photocatalytic cleaning process markedly enhanced cellular early response.Conclusion: The photocatalysis of TiO2-B＠anatase NWs for the removal of contamination from titanium surfaces has the potential to enable the rapid and complete establishment of early osseointegration.Keywords: photocatalysis, nanowires, TiO2, titanium implant, osseointegration |
| first_indexed | 2024-12-19T04:45:17Z |
| format | Article |
| id | doaj.art-fc0b32b6dcde4d189f3cdefb705327d5 |
| institution | Directory Open Access Journal |
| issn | 1178-2013 |
| language | English |
| last_indexed | 2024-12-19T04:45:17Z |
| publishDate | 2020-12-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Journal of Nanomedicine |
| spelling | doaj.art-fc0b32b6dcde4d189f3cdefb705327d52022-12-21T20:35:31ZengDove Medical PressInternational Journal of Nanomedicine1178-20132020-12-01Volume 159639965559939The Cleaning Effect of the Photocatalysis of TiO2-B＠anatase Nanowires on Biological Activity on a Titanium SurfaceGao YLin XZhao YXu SLai CGuo ZWu WDing XJia FZhou LLiu YYan Gao,1 Xi Lin,1 Yadong Zhao,2 Shulan Xu,1 Chunhua Lai,1 Zehong Guo,1 Wangxi Wu,1 Xianglong Ding,1 Fang Jia,1 Lei Zhou,1 Ying Liu3 1Center of Oral Implantology, Stomatological Hospital, Southern Medical University, Guangzhou 510280, People’s Republic of China; 2Department of Oral and Maxillofacial Surgery, Inner Mongolia People’ Hospital, Huhhot, Inner Mongolia 010017, People’s Republic of China; 3Department of Endodontics, Stomatological Hospital, Southern Medical University, Guangzhou 510280, People’s Republic of ChinaCorrespondence: Ying LiuDepartment of Endodontics, Stomatological Hospital, Southern Medical University, 366 South Jiang Nan Road, Hai Zhu District, Guangzhou 510280, People’s Republic of ChinaTel +86-20-84408890Fax +86-20-84433177Email 286668937@smu.edu.cnBackground: Improvements in the early osseointegration of titanium implants require investigations on the bone-implant interface, which is a critical and complex challenge. The surface cleanliness of titanium implants plays an important role at this interface. However, the implant surface would inevitably absorb contamination such as organic hydrocarbons, which is not conductive to the establishment of early osseointegration. Herein, an optimized approach for removing contamination from titanium surfaces was studied.Methods: The TiO2-B＠anatase NWs (nanowires) were prepared on titanium substrates through a hydrothermal process. A methylene blue degradation experiment was performed to assess the photodegradation activity. The cleaning effect of the photocatalysis of TiO2-B＠anatase NWs on a titanium surface and the cellular early response was determined by analyzing cell morphology, attachment, proliferation and differentiation.Results: The results indicated that the photocatalysis of TiO2-B＠anatase NWs could effectively remove hydrocarbons on titanium surfaces without sacrificing the favourable titanium surface morphology. The methylene blue degradation experiment revealed that the photocatalysis of TiO2-B＠anatase NWs had powerful degradation activity, which is attributed to the presence of strong oxidants such as ·OH. In addition, compared to the merely ultraviolet-treated titanium surfaces, the titanium surfaces treated after the NWs photocatalytic cleaning process markedly enhanced cellular early response.Conclusion: The photocatalysis of TiO2-B＠anatase NWs for the removal of contamination from titanium surfaces has the potential to enable the rapid and complete establishment of early osseointegration.Keywords: photocatalysis, nanowires, TiO2, titanium implant, osseointegrationhttps://www.dovepress.com/the-cleaning-effect-of-the-photocatalysis-of-tio2-banatase-nanowires-o-peer-reviewed-article-IJNphotocatalysisnanowirestio2titanium implantosseointegration |
| spellingShingle | Gao Y Lin X Zhao Y Xu S Lai C Guo Z Wu W Ding X Jia F Zhou L Liu Y The Cleaning Effect of the Photocatalysis of TiO2-B＠anatase Nanowires on Biological Activity on a Titanium Surface International Journal of Nanomedicine photocatalysis nanowires tio2 titanium implant osseointegration |
| title | The Cleaning Effect of the Photocatalysis of TiO2-B＠anatase Nanowires on Biological Activity on a Titanium Surface |
| title_full | The Cleaning Effect of the Photocatalysis of TiO2-B＠anatase Nanowires on Biological Activity on a Titanium Surface |
| title_fullStr | The Cleaning Effect of the Photocatalysis of TiO2-B＠anatase Nanowires on Biological Activity on a Titanium Surface |
| title_full_unstemmed | The Cleaning Effect of the Photocatalysis of TiO2-B＠anatase Nanowires on Biological Activity on a Titanium Surface |
| title_short | The Cleaning Effect of the Photocatalysis of TiO2-B＠anatase Nanowires on Biological Activity on a Titanium Surface |
| title_sort | cleaning effect of the photocatalysis of tio2 b anatase nanowires on biological activity on a titanium surface |
| topic | photocatalysis nanowires tio2 titanium implant osseointegration |
| url | https://www.dovepress.com/the-cleaning-effect-of-the-photocatalysis-of-tio2-banatase-nanowires-o-peer-reviewed-article-IJN |
| work_keys_str_mv | AT gaoy thecleaningeffectofthephotocatalysisoftio2banatasenanowiresonbiologicalactivityonatitaniumsurface AT linx thecleaningeffectofthephotocatalysisoftio2banatasenanowiresonbiologicalactivityonatitaniumsurface AT zhaoy thecleaningeffectofthephotocatalysisoftio2banatasenanowiresonbiologicalactivityonatitaniumsurface AT xus thecleaningeffectofthephotocatalysisoftio2banatasenanowiresonbiologicalactivityonatitaniumsurface AT laic thecleaningeffectofthephotocatalysisoftio2banatasenanowiresonbiologicalactivityonatitaniumsurface AT guoz thecleaningeffectofthephotocatalysisoftio2banatasenanowiresonbiologicalactivityonatitaniumsurface AT wuw thecleaningeffectofthephotocatalysisoftio2banatasenanowiresonbiologicalactivityonatitaniumsurface AT dingx thecleaningeffectofthephotocatalysisoftio2banatasenanowiresonbiologicalactivityonatitaniumsurface AT jiaf thecleaningeffectofthephotocatalysisoftio2banatasenanowiresonbiologicalactivityonatitaniumsurface AT zhoul thecleaningeffectofthephotocatalysisoftio2banatasenanowiresonbiologicalactivityonatitaniumsurface AT liuy thecleaningeffectofthephotocatalysisoftio2banatasenanowiresonbiologicalactivityonatitaniumsurface AT gaoy cleaningeffectofthephotocatalysisoftio2banatasenanowiresonbiologicalactivityonatitaniumsurface AT linx cleaningeffectofthephotocatalysisoftio2banatasenanowiresonbiologicalactivityonatitaniumsurface AT zhaoy cleaningeffectofthephotocatalysisoftio2banatasenanowiresonbiologicalactivityonatitaniumsurface AT xus cleaningeffectofthephotocatalysisoftio2banatasenanowiresonbiologicalactivityonatitaniumsurface AT laic cleaningeffectofthephotocatalysisoftio2banatasenanowiresonbiologicalactivityonatitaniumsurface AT guoz cleaningeffectofthephotocatalysisoftio2banatasenanowiresonbiologicalactivityonatitaniumsurface AT wuw cleaningeffectofthephotocatalysisoftio2banatasenanowiresonbiologicalactivityonatitaniumsurface AT dingx cleaningeffectofthephotocatalysisoftio2banatasenanowiresonbiologicalactivityonatitaniumsurface AT jiaf cleaningeffectofthephotocatalysisoftio2banatasenanowiresonbiologicalactivityonatitaniumsurface AT zhoul cleaningeffectofthephotocatalysisoftio2banatasenanowiresonbiologicalactivityonatitaniumsurface AT liuy cleaningeffectofthephotocatalysisoftio2banatasenanowiresonbiologicalactivityonatitaniumsurface |