Bihemispheric motor cortex transcranial direct current stimulation improves force steadiness in post-stroke hemiparetic patients: a randomized crossover controlled trial
Post-stroke patients usually exhibit reduced peak muscular torque (PT) and/or force steadiness during submaximal exercise. Brain stimulation techniques have been proposed to improve neural plasticity and help to restore motor performance in post-stroke patients. The present study compared the effect...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2016-08-01
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| Series: | Frontiers in Human Neuroscience |
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| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnhum.2016.00426/full |
| _version_ | 1819138134350233600 |
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| author | Rafael Ayres Montenegro Rafael Ayres Montenegro Adrian Midgley Renato Massaferri Wendell Bernardes ALEXANDRE HIDEKI OKANO Paulo Farinatti Paulo Farinatti |
| author_facet | Rafael Ayres Montenegro Rafael Ayres Montenegro Adrian Midgley Renato Massaferri Wendell Bernardes ALEXANDRE HIDEKI OKANO Paulo Farinatti Paulo Farinatti |
| author_sort | Rafael Ayres Montenegro |
| collection | DOAJ |
| description | Post-stroke patients usually exhibit reduced peak muscular torque (PT) and/or force steadiness during submaximal exercise. Brain stimulation techniques have been proposed to improve neural plasticity and help to restore motor performance in post-stroke patients. The present study compared the effects of bihemispheric motor cortex transcranial direct current stimulation (tDCS) on PT and force steadiness during maximal and submaximal resistance exercise performed by post-stroke patients vs. healthy controls. A double-blind randomized crossover controlled trial (identification number: TCTR20151112001; URL: http://www.clinicaltrials.in.th/) was conducted involving nine healthy and ten post-stroke hemiparetic individuals who received either tDCS (2 mA) or sham stimulus upon motor cortex for 20 min. PT and force steadiness (reflected by the coefficient of variation of muscular torque) were assessed during unilateral knee extension and flexion at maximal and submaximal workloads (1 set of 3 reps at 100% PT and 2 sets of 10 repetitions at 50% PT, respectively). No significant change in PT was observed in post-stroke and healthy subjects. Force steadiness during knee extension (~25-35%, P<0.001) and flexion (~22-33%, P<0.001) improved after tDCS compared to the sham condition in post-stroke patients, but improved only during knee extension (~13-27%, P<0.001) in healthy controls. These results suggest that tDCS may improve force steadiness, but not PT in post-stroke hemiparetic patients, which might be relevant in the context of motor rehabilitation programs. |
| first_indexed | 2024-12-22T11:01:56Z |
| format | Article |
| id | doaj.art-fc0ed76e1d174b16a94d577629a251a5 |
| institution | Directory Open Access Journal |
| issn | 1662-5161 |
| language | English |
| last_indexed | 2024-12-22T11:01:56Z |
| publishDate | 2016-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Human Neuroscience |
| spelling | doaj.art-fc0ed76e1d174b16a94d577629a251a52022-12-21T18:28:29ZengFrontiers Media S.A.Frontiers in Human Neuroscience1662-51612016-08-011010.3389/fnhum.2016.00426193345Bihemispheric motor cortex transcranial direct current stimulation improves force steadiness in post-stroke hemiparetic patients: a randomized crossover controlled trialRafael Ayres Montenegro0Rafael Ayres Montenegro1Adrian Midgley2Renato Massaferri3Wendell Bernardes4ALEXANDRE HIDEKI OKANO5Paulo Farinatti6Paulo Farinatti7Laboratory of Physical Activity and Health Promotion, Institute of Physical Education and Sports, University of Rio de Janeiro StateGraduate Program in Clinical and Experimental Physiopathology, Faculty of Medical Sciences, University of Rio de Janeiro StateEdge Hill UniversityLaboratory of Physical Activity and Health Promotion, Institute of Physical Education and Sports, University of Rio de Janeiro StateLaboratory of Physical Activity and Health Promotion, Institute of Physical Education and Sports, University of Rio de Janeiro StateFederal University of Rio Grande do NorteLaboratory of Physical Activity and Health Promotion, Institute of Physical Education and Sports, University of Rio de Janeiro StateGraduate Program in Clinical and Experimental Physiopathology, Faculty of Medical Sciences, University of Rio de Janeiro StatePost-stroke patients usually exhibit reduced peak muscular torque (PT) and/or force steadiness during submaximal exercise. Brain stimulation techniques have been proposed to improve neural plasticity and help to restore motor performance in post-stroke patients. The present study compared the effects of bihemispheric motor cortex transcranial direct current stimulation (tDCS) on PT and force steadiness during maximal and submaximal resistance exercise performed by post-stroke patients vs. healthy controls. A double-blind randomized crossover controlled trial (identification number: TCTR20151112001; URL: http://www.clinicaltrials.in.th/) was conducted involving nine healthy and ten post-stroke hemiparetic individuals who received either tDCS (2 mA) or sham stimulus upon motor cortex for 20 min. PT and force steadiness (reflected by the coefficient of variation of muscular torque) were assessed during unilateral knee extension and flexion at maximal and submaximal workloads (1 set of 3 reps at 100% PT and 2 sets of 10 repetitions at 50% PT, respectively). No significant change in PT was observed in post-stroke and healthy subjects. Force steadiness during knee extension (~25-35%, P<0.001) and flexion (~22-33%, P<0.001) improved after tDCS compared to the sham condition in post-stroke patients, but improved only during knee extension (~13-27%, P<0.001) in healthy controls. These results suggest that tDCS may improve force steadiness, but not PT in post-stroke hemiparetic patients, which might be relevant in the context of motor rehabilitation programs.http://journal.frontiersin.org/Journal/10.3389/fnhum.2016.00426/fullMotor CortexStroketDCSperformancestrengthPhysical rehabilitation |
| spellingShingle | Rafael Ayres Montenegro Rafael Ayres Montenegro Adrian Midgley Renato Massaferri Wendell Bernardes ALEXANDRE HIDEKI OKANO Paulo Farinatti Paulo Farinatti Bihemispheric motor cortex transcranial direct current stimulation improves force steadiness in post-stroke hemiparetic patients: a randomized crossover controlled trial Frontiers in Human Neuroscience Motor Cortex Stroke tDCS performance strength Physical rehabilitation |
| title | Bihemispheric motor cortex transcranial direct current stimulation improves force steadiness in post-stroke hemiparetic patients: a randomized crossover controlled trial |
| title_full | Bihemispheric motor cortex transcranial direct current stimulation improves force steadiness in post-stroke hemiparetic patients: a randomized crossover controlled trial |
| title_fullStr | Bihemispheric motor cortex transcranial direct current stimulation improves force steadiness in post-stroke hemiparetic patients: a randomized crossover controlled trial |
| title_full_unstemmed | Bihemispheric motor cortex transcranial direct current stimulation improves force steadiness in post-stroke hemiparetic patients: a randomized crossover controlled trial |
| title_short | Bihemispheric motor cortex transcranial direct current stimulation improves force steadiness in post-stroke hemiparetic patients: a randomized crossover controlled trial |
| title_sort | bihemispheric motor cortex transcranial direct current stimulation improves force steadiness in post stroke hemiparetic patients a randomized crossover controlled trial |
| topic | Motor Cortex Stroke tDCS performance strength Physical rehabilitation |
| url | http://journal.frontiersin.org/Journal/10.3389/fnhum.2016.00426/full |
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