Response predictors to treatment with pegylated interferon in chronic hepatitis B
The clinical and epidemiological importance of chronic B hepatitis is currently unquestionable as a cause of end-stage liver disease and hepatocellular carcinoma. Recently, predictors of treatment response of this disease have been studied, both before and during the course of medication. Therapy st...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
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| Series: | Brazilian Journal of Infectious Diseases |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000500017&lng=en&tlng=en |
| _version_ | 1818112434245730304 |
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| author | Paulo Roberto Abrão Ferreira Simone de Barros Tenore |
| author_facet | Paulo Roberto Abrão Ferreira Simone de Barros Tenore |
| author_sort | Paulo Roberto Abrão Ferreira |
| collection | DOAJ |
| description | The clinical and epidemiological importance of chronic B hepatitis is currently unquestionable as a cause of end-stage liver disease and hepatocellular carcinoma. Recently, predictors of treatment response of this disease have been studied, both before and during the course of medication. Therapy stopping rules have been proposed, which may be useful in patients presenting poor treatment tolerance. This review discusses the treatment response predictors usefulness, with emphasis on ALT, quantitative HBsAg and HBeAg, quantitative HBV-DNA and HBV genotype |
| first_indexed | 2024-12-11T03:18:52Z |
| format | Article |
| id | doaj.art-fc1532e24ada4137980f3efe99277c3b |
| institution | Directory Open Access Journal |
| issn | 1678-4391 |
| language | English |
| last_indexed | 2024-12-11T03:18:52Z |
| publisher | Elsevier |
| record_format | Article |
| series | Brazilian Journal of Infectious Diseases |
| spelling | doaj.art-fc1532e24ada4137980f3efe99277c3b2022-12-22T01:22:41ZengElsevierBrazilian Journal of Infectious Diseases1678-439114551952510.1590/S1413-86702010000500017S1413-86702010000500017Response predictors to treatment with pegylated interferon in chronic hepatitis BPaulo Roberto Abrão Ferreira0Simone de Barros Tenore1Universidade Federal de São PauloUniversidade Federal de São PauloThe clinical and epidemiological importance of chronic B hepatitis is currently unquestionable as a cause of end-stage liver disease and hepatocellular carcinoma. Recently, predictors of treatment response of this disease have been studied, both before and during the course of medication. Therapy stopping rules have been proposed, which may be useful in patients presenting poor treatment tolerance. This review discusses the treatment response predictors usefulness, with emphasis on ALT, quantitative HBsAg and HBeAg, quantitative HBV-DNA and HBV genotypehttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000500017&lng=en&tlng=enhepatitis BHBsAgHBeAgHBV-DNApegylated interferon |
| spellingShingle | Paulo Roberto Abrão Ferreira Simone de Barros Tenore Response predictors to treatment with pegylated interferon in chronic hepatitis B Brazilian Journal of Infectious Diseases hepatitis B HBsAg HBeAg HBV-DNA pegylated interferon |
| title | Response predictors to treatment with pegylated interferon in chronic hepatitis B |
| title_full | Response predictors to treatment with pegylated interferon in chronic hepatitis B |
| title_fullStr | Response predictors to treatment with pegylated interferon in chronic hepatitis B |
| title_full_unstemmed | Response predictors to treatment with pegylated interferon in chronic hepatitis B |
| title_short | Response predictors to treatment with pegylated interferon in chronic hepatitis B |
| title_sort | response predictors to treatment with pegylated interferon in chronic hepatitis b |
| topic | hepatitis B HBsAg HBeAg HBV-DNA pegylated interferon |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000500017&lng=en&tlng=en |
| work_keys_str_mv | AT paulorobertoabraoferreira responsepredictorstotreatmentwithpegylatedinterferoninchronichepatitisb AT simonedebarrostenore responsepredictorstotreatmentwithpegylatedinterferoninchronichepatitisb |