Type 2 Diabetes Risk and Lipid Metabolism Related to the Pleiotropic Effects of an <i>ABCB1</i> Variant: A Chinese Family-Based Cohort Study

Type 2 Diabetes Risk and Lipid Metabolism Related to the Pleiotropic Effects of an <i>ABCB1</i> Variant: A Chinese Family-Based Cohort Study

The single nucleotide polymorphism (SNP) rs4148727 in <i>ABCB1</i> (encoding p-glycoprotein) is associated with lipid levels; however, its association with type 2 diabetes (T2DM) and its the genetic correlation with lipid profiles and T2DM are unclear. We included 2300 participants from...

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Bibliographic Details
Main Authors: Junhui Wu, Xiaowen Wang, Hongbo Chen, Ruotong Yang, Huan Yu, Yiqun Wu, Yonghua Hu
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Metabolites
Subjects:
pleiotropic effects
lipid profiles
type 2 diabetes
mediation
Online Access:https://www.mdpi.com/2218-1989/12/9/875

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