Syphilitic Gummata in the Central Nervous System: A Narrative Review and Case Report about a Noteworthy Clinical Manifestation
Infection with <i>Treponema pallidum</i> is on the rise. In this narrative literature review, we show that the incidence of rare manifestations of syphilis, such as intracerebral gummata, is increasing and should be considered in the differential diagnosis of intracerebral lesions. With...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-04-01
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| Series: | Microorganisms |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-2607/9/5/906 |
| _version_ | 1827694316258066432 |
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| author | Lennart Barthel Susann Hetze Sarah Teuber-Hanselmann Valérie Chapot Ulrich Sure |
| author_facet | Lennart Barthel Susann Hetze Sarah Teuber-Hanselmann Valérie Chapot Ulrich Sure |
| author_sort | Lennart Barthel |
| collection | DOAJ |
| description | Infection with <i>Treponema pallidum</i> is on the rise. In this narrative literature review, we show that the incidence of rare manifestations of syphilis, such as intracerebral gummata, is increasing and should be considered in the differential diagnosis of intracerebral lesions. With the exemplary case that we present here, we aim to raise awareness of the resurgence of this disease, which should be considered in the differential diagnosis of intracerebral lesions, especially for patients who have a risk profile for syphilis, and serological testing for <i>T. pallidum</i> prior to surgery should be discussed in order to avoid an unnecessary operation. |
| first_indexed | 2024-03-10T12:02:24Z |
| format | Article |
| id | doaj.art-fc192aee24b44619a50a18a04c6279d2 |
| institution | Directory Open Access Journal |
| issn | 2076-2607 |
| language | English |
| last_indexed | 2024-03-10T12:02:24Z |
| publishDate | 2021-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj.art-fc192aee24b44619a50a18a04c6279d22023-11-21T16:54:56ZengMDPI AGMicroorganisms2076-26072021-04-019590610.3390/microorganisms9050906Syphilitic Gummata in the Central Nervous System: A Narrative Review and Case Report about a Noteworthy Clinical ManifestationLennart Barthel0Susann Hetze1Sarah Teuber-Hanselmann2Valérie Chapot3Ulrich Sure4Department of Neurosurgery, University Hospital of Essen, Hufelandstraße 55, 45147 Essen, GermanyDepartment of Neurosurgery, University Hospital of Essen, Hufelandstraße 55, 45147 Essen, GermanyInstitute of Neuropathology, University Hospital of Essen, Hufelandstraße 55, 45147 Essen, GermanyInstitute of Medical Microbiology, University Hospital of Essen, Hufelandstraße 55, 45147 Essen, GermanyDepartment of Neurosurgery, University Hospital of Essen, Hufelandstraße 55, 45147 Essen, GermanyInfection with <i>Treponema pallidum</i> is on the rise. In this narrative literature review, we show that the incidence of rare manifestations of syphilis, such as intracerebral gummata, is increasing and should be considered in the differential diagnosis of intracerebral lesions. With the exemplary case that we present here, we aim to raise awareness of the resurgence of this disease, which should be considered in the differential diagnosis of intracerebral lesions, especially for patients who have a risk profile for syphilis, and serological testing for <i>T. pallidum</i> prior to surgery should be discussed in order to avoid an unnecessary operation.https://www.mdpi.com/2076-2607/9/5/906neurosyphilissyphilistreponema pallidumsyphilitic gummacentral nervous system gummacerebral syphilitic gumma |
| spellingShingle | Lennart Barthel Susann Hetze Sarah Teuber-Hanselmann Valérie Chapot Ulrich Sure Syphilitic Gummata in the Central Nervous System: A Narrative Review and Case Report about a Noteworthy Clinical Manifestation Microorganisms neurosyphilis syphilis treponema pallidum syphilitic gumma central nervous system gumma cerebral syphilitic gumma |
| title | Syphilitic Gummata in the Central Nervous System: A Narrative Review and Case Report about a Noteworthy Clinical Manifestation |
| title_full | Syphilitic Gummata in the Central Nervous System: A Narrative Review and Case Report about a Noteworthy Clinical Manifestation |
| title_fullStr | Syphilitic Gummata in the Central Nervous System: A Narrative Review and Case Report about a Noteworthy Clinical Manifestation |
| title_full_unstemmed | Syphilitic Gummata in the Central Nervous System: A Narrative Review and Case Report about a Noteworthy Clinical Manifestation |
| title_short | Syphilitic Gummata in the Central Nervous System: A Narrative Review and Case Report about a Noteworthy Clinical Manifestation |
| title_sort | syphilitic gummata in the central nervous system a narrative review and case report about a noteworthy clinical manifestation |
| topic | neurosyphilis syphilis treponema pallidum syphilitic gumma central nervous system gumma cerebral syphilitic gumma |
| url | https://www.mdpi.com/2076-2607/9/5/906 |
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