Pure <i>Trans</i>-Resveratrol Nanoparticles Prepared by a Supercritical Antisolvent Process Using Alcohol and Dichloromethane Mixtures: Effect of Particle Size on Dissolution and Bioavailability in Rats

Pure <i>Trans</i>-Resveratrol Nanoparticles Prepared by a Supercritical Antisolvent Process Using Alcohol and Dichloromethane Mixtures: Effect of Particle Size on Dissolution and Bioavailability in Rats

The aim of this study was to prepare pure <i>trans</i>-resveratrol nanoparticles without additives (surfactants, polymers, and sugars) using a supercritical antisolvent (SAS) process with alcohol (methanol or ethanol) and dichloromethane mixtures. In addition, in order to investigate the...

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Bibliographic Details
Main Authors: Eun-Sol Ha, Heejun Park, Seon-Kwang Lee, Woo-Yong Sim, Ji-Su Jeong, In-hwan Baek, Min-Soo Kim
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Antioxidants
Subjects:
resveratrol
nanoparticle
supercritical fluid
dissolution
bioavailability
Online Access:https://www.mdpi.com/2076-3921/9/4/342

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